Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P47985 | UQCRFS1 | Cytochrome b-c1 complex subunit Rieske, … | Homo sapiens (Human) | 274 aa |
Protein Details: P47985 (UQCRFS1)
Protein Information
| Accession | P47985 |
|---|---|
| Protein Names | Cytochrome b-c1 complex subunit Rieske, mitochondrial (EC 7.1.1.8) (Complex III subunit 5) (Cytochrome b-c1 complex subunit 5) (Rieske iron-sulfur protein) (RISP) (Rieske protein UQCRFS1) (Ubiquinol-cytochrome c reductase iron-sulfur subunit) [Cleaved into: Cytochrome b-c1 complex subunit 9 (Su9) (Subunit 9) (8 kDa subunit 9) (Complex III subunit IX) (Cytochrome b-c1 complex subunit 11) (UQCRFS1 mitochondrial targeting sequence) (UQCRFS1 MTS) (Ubiquinol-cytochrome c reductase 8 kDa protein)] |
| Gene Symbol | UQCRFS1 |
| Organism | Homo sapiens (Human) |
| Length | 274 aa |
| Isoforms | No isoforms |
| Related PMIDs | 24357059 31251020 32944167 33636221 36430497 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MLSVASRSGP11FAPVLSATSR21GVAGALRPLV31QATVPATPEQ41PVLDLKRPFL
51-10051SRESLSGQAV61RRPLVASVGL71NVPASVCYSH81TDIKVPDFSE91YRRLEVLDST
101-150101KSSRESSEAR111KGFSYLVTGV121TTVGVAYAAK131NAVTQFVSSM141SASADVLALA
151-200151KIEIKLSDIP161EGKNMAFKWR171GKPLFVRHRT181QKEIEQEAAV191ELSQLRDPQH
201-250201DLDRVKKPEW211VILIGVCTHL221GCVPIANAGD231FGGYYCPCHG241SHYDASGRIR
251-274251LGPAPLNLEV261PTYEFTSDDM271VIVG
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 77 | - | - | - |
Deep-Palm: 0.96
|
|
| 217 | - | - | - |
Deep-Palm: 0.70
|
|
| 222 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.41
|
|
| 236 | - | - | - |
Deep-Palm: 0.19
|
|
| 238 | - | - | - |
Deep-Palm: 0.31
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.364
4
cerebral cortex
Specificity: 0.364
4/4 (100.0%)
3
LNCaP
Specificity: 0.273
3/3 (100.0%)
2
PC3
Specificity: 0.182
2/2 (100.0%)
1
heart
Specificity: 0.091
1/1 (100.0%)
1
HUVECs
Specificity: 0.091
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 89 | S → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 177 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 215 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 238 | C → C | 0.001887 | SNP | Silent | UCEC |