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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P47985 UQCRFS1 Cytochrome b-c1 complex subunit Rieske, … Homo sapiens (Human) 274 aa

Protein Details: P47985 (UQCRFS1)

Protein Information
Accession P47985
Protein Names Cytochrome b-c1 complex subunit Rieske, mitochondrial (EC 7.1.1.8) (Complex III subunit 5) (Cytochrome b-c1 complex subunit 5) (Rieske iron-sulfur protein) (RISP) (Rieske protein UQCRFS1) (Ubiquinol-cytochrome c reductase iron-sulfur subunit) [Cleaved into: Cytochrome b-c1 complex subunit 9 (Su9) (Subunit 9) (8 kDa subunit 9) (Complex III subunit IX) (Cytochrome b-c1 complex subunit 11) (UQCRFS1 mitochondrial targeting sequence) (UQCRFS1 MTS) (Ubiquinol-cytochrome c reductase 8 kDa protein)]
Gene Symbol UQCRFS1
Organism Homo sapiens (Human)
Length 274 aa
Isoforms No isoforms
Related PMIDs 24357059 31251020 32944167 33636221 36430497
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.814
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
35
LNCaP cells
Specificity: 0.814
35/46 (76.1%)
4
Cerebral cortex
Specificity: 0.093
4/4 (100.0%)
2
PC3 cells
Specificity: 0.047
2/4 (50.0%)
1
Endothelial cells
Specificity: 0.023
1/2 (50.0%)
1
Liver membrane
Specificity: 0.023
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MLSVASRSGP11FAPVLSATSR21GVAGALRPLV31QATVPATPEQ41PVLDLKRPFL
51-10051SRESLSGQAV61RRPLVASVGL71NVPASVCYSH81TDIKVPDFSE91YRRLEVLDST
101-150101KSSRESSEAR111KGFSYLVTGV121TTVGVAYAAK131NAVTQFVSSM141SASADVLALA
151-200151KIEIKLSDIP161EGKNMAFKWR171GKPLFVRHRT181QKEIEQEAAV191ELSQLRDPQH
201-250201DLDRVKKPEW211VILIGVCTHL221GCVPIANAGD231FGGYYCPCHG241SHYDASGRIR
251-274251LGPAPLNLEV261PTYEFTSDDM271VIVG
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
222 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
89 S → C 0.002427 SNP Missense Mutation BLCA
177 R → C 0.001887 SNP Missense Mutation UCEC
215 G → C 0.001887 SNP Missense Mutation UCEC
238 C → C 0.001887 SNP Silent UCEC