Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P48023 | FASLG | Tumor necrosis factor ligand superfamily … | Homo sapiens (Human) | 281 aa |
Protein Details: P48023 (FASLG)
Protein Information
| Accession | P48023 |
|---|---|
| Protein Names | Tumor necrosis factor ligand superfamily member 6 (Apoptosis antigen ligand) (APTL) (CD95 ligand) (CD95-L) (Fas antigen ligand) (Fas ligand) (FasL) (CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form (Receptor-binding FasL ectodomain) (Soluble Fas ligand) (sFasL); ADAM10-processed FasL form (APL); FasL intracellular domain (FasL ICD) (SPPL2A-processed FasL form) (SPA)] |
| Gene Symbol | FASLG |
| Organism | Homo sapiens (Human) |
| Length | 281 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MQQPFNYPYP11QIYWVDSSAS21SPWAPPGTVL31PCPTSVPRRP41GQRRPPPPPP
51-10051PPPLPPPPPP61PPLPPLPLPP71LKKRGNHSTG81LCLLVMFFMV91LVALVGLGLG
101-150101MFQLFHLQKE111LAELRESTSQ121MHTASSLEKQ131IGHPSPPPEK141KELRKVAHLT
151-200151GKSNSRSMPL161EWEDTYGIVL171LSGVKYKKGG181LVINETGLYF191VYSKVYFRGQ
201-250201SCNNLPLSHK211VYMRNSKYPQ221DLVMMEGKMM231SYCTTGQMWA241RSSYLGAVFN
251-281251LTSADHLYVN261VSELSLVNFE271ESQTFFGLYK281L
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 32 | - | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.92
|
|
| 82 | DBPTM SWISSPALM | - | - | - |
Deep-Palm: 0.95
|
| 202 | - | - | - |
Deep-Palm: 0.15
|
|
| 233 | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.43
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 176 | Y → C | 0.002545 | SNP | Missense Mutation | GBM |
| 202 | C → C | 0.005435 | SNP | Silent | ESCA |