Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P48318 | Gad1 | Glutamate decarboxylase 1 (EC 4.1.1.15) … | Mus musculus (Mouse) | 593 aa |
Protein Details: P48318 (Gad1)
Protein Information
| Accession | P48318 |
|---|---|
| Protein Names | Glutamate decarboxylase 1 (EC 4.1.1.15) (67 kDa glutamic acid decarboxylase) (GAD-67) (Glutamate decarboxylase 67 kDa isoform) |
| Gene Symbol | Gad1 |
| Organism | Mus musculus (Mouse) |
| Length | 593 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29660268 29733200 34200797 35358180 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MASSTPSPAT11SSNAGADPNT21TNLRPTTYDT31WCGVAHGCTR41KLGLKICGFL
51-10051QRTNSLEEKS61RLVSAFRERQ71SSKNLLSCEN81SDQGARFRRT91ETDFSNLFAQ
101-150101DLLPAKNGEE111QTAQFLLEVV121DILLNYVRKT131FDRSTKVLDF141HHPHQLLEGM
151-200151EGFNLELSDH161PESLEQILVD171CRDTLKYGVR181TGHPRFFNQL191STGLDIIGLA
201-250201GEWLTSTANT211NMFTYEIAPV221FVLMEQITLK231KMREIVGWSN241KDGDGIFSPG
251-300251GAISNMYSIM261AARYKYFPEV271KTKGMAAVPK281LVLFTSEHSH291YSIKKAGAAL
301-350301GFGTDNVILI311KCNERGKIIP321ADLEAKILDA331KQKGYVPLYV341NATAGTTVYG
351-400351AFDPIQEIAD361ICEKYNLWLH371VDAAWGGGLL381MSRKHRHKLS391GIERANSVTW
401-450401NPHKMMGVLL411QCSAILVKEK421GILQGCNQMC431AGYLFQPDKQ441YDVSYDTGDK
451-500451AIQCGRHVDI461FKFWLMWKAK471GTVGFENQIN481KCLELADYLY491AKIKNREEFE
501-550501MVFDGEPEHT511NVCFWYIPQS521LRGVPDSPER531REKLHRVAPK541IKALMMESGT
551-593551TMVGYQPQGD561KANFFRMVIS571NPAATQSDID581FLIEEIERLG591QDL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 32 | SWISSPALM DBPTM CYSMODDB | - |
Forebrain
(28680068)
| - |
Deep-Palm: 0.68
|
| 38 | SWISSPALM DBPTM CYSMODDB | - |
Forebrain
(28680068)
| - |
GPS-Palm: 0.82
Deep-Palm: 0.83
|
| 47 | - |
brain
(39008777)
|
Brain
(35358180)
|
GPS-Palm: 0.94
Deep-Palm: 0.95
|
|
| 78 | - |
brain
(39008777)
|
Brain
(35358180)
|
GPS-Palm: 0.71
Deep-Palm: 0.88
|
|
| 171 | - | - | - |
Deep-Palm: 0.85
|
|
| 312 | - | - | - |
Deep-Palm: 0.95
|
|
| 362 | - | - | - |
Deep-Palm: 0.25
|
|
| 412 | - | - | - |
GPS-Palm: 0.85
Deep-Palm: 0.90
|
|
| 426 | SWISSPALM DBPTM CYSMODDB | Pyridoxal-dependent decarboxylase conserved domain |
Forebrain
(28680068)
|
Brain
(35358180)
|
GPS-Palm: 0.83
Deep-Palm: 0.90
|
| 430 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.80
Deep-Palm: 0.70
|
|
| 454 | - | - | - |
Deep-Palm: 0.12
|
|
| 482 | - | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.87
|
|
| 513 | - | - | - |
Deep-Palm: 0.08
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Brain
Specificity: 0.129
4/4 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
27
Brain tissue (Mass)
Specificity: 0.871
27/56 (48.2%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.