Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P48320 | Gad2 | Glutamate decarboxylase 2 (EC 4.1.1.15) … | Mus musculus (Mouse) | 585 aa |
Protein Details: P48320 (Gad2)
Protein Information
| Accession | P48320 |
|---|---|
| Protein Names | Glutamate decarboxylase 2 (EC 4.1.1.15) (65 kDa glutamic acid decarboxylase) (GAD-65) (Glutamate decarboxylase 65 kDa isoform) |
| Gene Symbol | Gad2 |
| Organism | Mus musculus (Mouse) |
| Length | 585 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29660268 29733200 34200797 35358180 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MASPGSGFWS11FGSEDGSADP21ENPGTARAWC31QVAQKFTGGI41GNKLCALLYG
51-10051DSGKPAEGGG61SVTSRAATGK71VACTCDQKPC81NCPKGDVNYA91FLHATDLLPA
101-150101CDGERPTLAF111LQDVMNILLQ121YVVKSFDRST131KVIDFHYPNE141LLQEYNWELA
151-200151DQPQNLEEIL161THCQTTLKYA171IKTGHPRYFN181QLSTGLDMVG191LAADWLTSTA
201-250201NTNMFTYEIA211PVFVLLEYVT221LKKMREIIGW231PGGSGDGIFS241PGGAISNMYA
251-300251MLIARYKMFP261EVKEKGMAAV271PRLIAFTSEH281SHFSLKKGAA291ALGIGTDSVI
301-350301LIKCDERGKM311IPSDLERRIL321EVKQKGFVPF331LVSATAGTTV341YGAFDPLLAV
351-400351ADICKKYKIW361MHVDAAWGGG371LLMSRKHKWK381LSGVERANSV391TWNPHKMMGV
401-450401PLQCSALLVR411EEGLMQSCNQ421MHASYLFQQD431KHYDLSYDTG441DKALQCGRHV
451-500451DVFKLWLMWR461AKGTTGFEAH471IDKCLELAEY481LYTIIKNREG491YEMVFDGKPQ
501-550501HTNVCFWFVP511PSLRTLEDNE521ERMSRLSKVA531PVIKARMMEY541GTTMVSYQPL
551-585551GDKVNFFRMV561ISNPAATHQD571IDFLIEEIER581LGQDL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 30 | - |
Brain
(34200797)
|
Brain
(35358180)
|
Deep-Palm: 0.87
|
|
| 45 | - |
Brain
(34200797)
|
Brain
(35358180)
|
GPS-Palm: 0.92
Deep-Palm: 0.97
|
|
| 73 | - |
Brain
(34200797)
| - |
Deep-Palm: 0.38
|
|
| 75 | - |
Brain
(34200797)
| - |
GPS-Palm: 0.78
Deep-Palm: 0.17
|
|
| 80 | - |
Brain
(34200797)
| - |
Deep-Palm: 0.07
|
|
| 82 | - |
Brain
(34200797)
| - |
Deep-Palm: 0.06
|
|
| 101 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.67
Deep-Palm: 0.88
|
|
| 163 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.82
Deep-Palm: 0.73
|
|
| 304 | - | - | - |
Deep-Palm: 0.96
|
|
| 354 | - | - | - |
Deep-Palm: 0.65
|
|
| 404 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.81
Deep-Palm: 0.74
|
|
| 418 | SWISSPALM DBPTM CYSMODDB | Pyridoxal-dependent decarboxylase conserved domain |
Forebrain
(28680068)
|
Brain
(35358180)
|
GPS-Palm: 0.69
Deep-Palm: 0.45
|
| 446 | - | - | - |
GPS-Palm: 0.66
Deep-Palm: 0.52
|
|
| 474 | - | - | - |
Deep-Palm: 0.83
|
|
| 505 | - | - | - |
Deep-Palm: 0.17
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
5
Brain
Specificity: 0.172
5/5 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
24
Brain tissue (Mass)
Specificity: 0.828
24/56 (42.9%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.