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UniProt ID Gene Symbol Protein Name Organism Length Action
P48509 CD151 CD151 antigen (GP27) (Membrane glycoprotein … Homo sapiens (Human) 253 aa

Protein Details: P48509 (CD151)

Protein Information
AccessionP48509
Protein NamesCD151 antigen (GP27) (Membrane glycoprotein SFA-1) (Platelet-endothelial tetraspan antigen 3) (PETA-3) (Tetraspanin-24) (Tspan-24) (CD antigen CD151)
Gene SymbolCD151
OrganismHomo sapiens (Human)
Length253 aa
IsoformsNo isoforms
Related PMIDs 24357059 26111759 29733200 31251020 33636221 31251020 (mass) 32651440 (mass) 36430497 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MGEFNEKKTT11CGTVCLKYLL21FTYNCCFWLA31GLAVMAVGIW41TLALKSDYIS
51-10051LLASGTYLAT61AYILVVAGTV71VMVTGVLGCC81ATFKERRNLL91RLYFILLLII
101-150101FLLEIIAGIL111AYAYYQQLNT121ELKENLKDTM131TKRYHQPGHE141AVTSAVDQLQ
151-200151QEFHCCGSNN161SQDWRDSEWI171RSQEAGGRVV181PDSCCKTVVA191LCGQRDHASN
201-250201IYKVEGGCIT211KLETFIQEHL221RVIGAVGIGI231ACVQVFGMIF241TCCLYRSLKL
251-253251EHY
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
11 DBPTM SWISSPALM - - -
GPS-Palm: 0.81
Deep-Palm: 0.02
15 DBPTM SWISSPALM - - -
GPS-Palm: 0.87
Deep-Palm: 0.10
25 - - -
GPS-Palm: 0.71
Deep-Palm: 0.61
26 - - -
GPS-Palm: 0.80
Deep-Palm: 0.56
79 DBPTM SWISSPALM Tetraspanin family - -
GPS-Palm: 0.95
Deep-Palm: 0.98
80 DBPTM SWISSPALM Tetraspanin family - -
GPS-Palm: 0.93
Deep-Palm: 0.98
155 - - -
Deep-Palm: 0.62
156 - - -
Deep-Palm: 0.57
184 SWISSPALM DBPTM CYSMODDB - - -
GPS-Palm: 0.83
Deep-Palm: 0.83
185 SWISSPALM DBPTM CYSMODDB - - -
GPS-Palm: 0.88
Deep-Palm: 0.87
192 SWISSPALM DBPTM CYSMODDB -
HeLa (29575903)
-
GPS-Palm: 0.80
Deep-Palm: 0.73
208 - - -
Deep-Palm: 0.81
232 - - -
Deep-Palm: 0.69
242 DBPTM SWISSPALM - - -
GPS-Palm: 0.96
Deep-Palm: 0.04
243 DBPTM SWISSPALM - - -
GPS-Palm: 0.95
Deep-Palm: 0.02
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.364
4
Primary T cell
Specificity: 0.333
4/4 (100.0%)
3
LNCaP
Specificity: 0.250
3/3 (100.0%)
1
HAP1 cell
Specificity: 0.083
1/1 (100.0%)
1
293T cell
Specificity: 0.083
1/1 (100.0%)
1
heart
Specificity: 0.083
1/1 (100.0%)
1
HUVECs
Specificity: 0.083
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP cells (Mass)
Specificity: 0.083
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
112 Y → C 0.003559 SNP Missense Mutation KIRP
184 C → Y 0.002033 SNP Missense Mutation LUSC
232 C → F 0.001764 SNP Missense Mutation LUAD