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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P48556 PSMD8 26S proteasome non-ATPase regulatory subunit … Homo sapiens (Human) 350 aa

Protein Details: P48556 (PSMD8)

Protein Information
Accession P48556
Protein Names 26S proteasome non-ATPase regulatory subunit 8 (26S proteasome regulatory subunit RPN12) (26S proteasome regulatory subunit S14) (p31)
Gene Symbol PSMD8
Organism Homo sapiens (Human)
Length 350 aa
Isoforms No isoforms
Related PMIDs 29733200
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
4
HAP1 cells
Specificity: 0.500
4/10 (40.0%)
4
293T cells
Specificity: 0.500
4/10 (40.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MFIKGRAPRA11PPRERRRATR21GGLRQVVAPP31RALGSTSRPH41FRRASVCRRR
51-10051CRKSGGLLAA61SRKMAAAAVN71GAAGFSSSGP81AATSGAVLQA91ATGMYEQLKG
101-150101EWNRKSPNLS111KCGEELGRLK121LVLLELNFLP131TTGTKLTKQQ141LILARDILEI
151-200151GAQWSILRKD161IPSFERYMAQ171LKCYYFDYKE181QLPESAYMHQ191LLGLNLLFLL
201-250201SQNRVAEFHT211ELERLPAKDI221QTNVYIKHPV231SLEQYLMEGS241YNKVFLAKGN
251-300251IPAESYTFFI261DILLDTIRDE271IAGCIEKAYE281KILFTEATRI291LFFNTPKKMT
301-350301DYAKKRGWVL311GPNNYYSFAS321QQQKPEDTTI331PSTELAKQVI341EYARQLEMIV
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
47 Prediction (Medium) - -
51 Prediction (Medium) - -
112 Prediction (Medium) - -
173 Prediction (Low) - -
274 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
112 C → W 0.005435 SNP Missense Mutation ESCA
158 R → C 0.001887 SNP Missense Mutation UCEC
201 S → C 0.002294 SNP Missense Mutation OV