Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P48556 | PSMD8 | 26S proteasome non-ATPase regulatory subunit … | Homo sapiens (Human) | 350 aa |
Protein Details: P48556 (PSMD8)
Protein Information
| Accession | P48556 |
|---|---|
| Protein Names | 26S proteasome non-ATPase regulatory subunit 8 (26S proteasome regulatory subunit RPN12) (26S proteasome regulatory subunit S14) (p31) |
| Gene Symbol | PSMD8 |
| Organism | Homo sapiens (Human) |
| Length | 350 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MFIKGRAPRA11PPRERRRATR21GGLRQVVAPP31RALGSTSRPH41FRRASVCRRR
51-10051CRKSGGLLAA61SRKMAAAAVN71GAAGFSSSGP81AATSGAVLQA91ATGMYEQLKG
101-150101EWNRKSPNLS111KCGEELGRLK121LVLLELNFLP131TTGTKLTKQQ141LILARDILEI
151-200151GAQWSILRKD161IPSFERYMAQ171LKCYYFDYKE181QLPESAYMHQ191LLGLNLLFLL
201-250201SQNRVAEFHT211ELERLPAKDI221QTNVYIKHPV231SLEQYLMEGS241YNKVFLAKGN
251-300251IPAESYTFFI261DILLDTIRDE271IAGCIEKAYE281KILFTEATRI291LFFNTPKKMT
301-350301DYAKKRGWVL311GPNNYYSFAS321QQQKPEDTTI331PSTELAKQVI341EYARQLEMIV
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 47 | - | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.96
|
|
| 51 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.94
|
|
| 112 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.97
|
|
| 173 | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.31
|
|
| 274 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.85
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
1
HAP1 cell
Specificity: 0.500
1/1 (100.0%)
1
293T cell
Specificity: 0.500
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 112 | C → W | 0.005435 | SNP | Missense Mutation | ESCA |
| 158 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 201 | S → C | 0.002294 | SNP | Missense Mutation | OV |