Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P48634 PRRC2A Protein PRRC2A (HLA-B-associated transcript 2) … Homo sapiens (Human) 2157 aa

Protein Details: P48634 (PRRC2A)

Protein Information
AccessionP48634
Protein NamesProtein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2)
Gene SymbolPRRC2A
OrganismHomo sapiens (Human)
Length2157 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MSDRSGPTAK11GKDGKKYSSL21NLFDTYKGKS31LEIQKPAVAP41RHGLQSLGKV
51-10051AIARRMPPPA61NLPSLKAENK71GNDPNVSLVP81KDGTGWASKQ91EQSDPKSSDA
101-150101STAQPPESQP111LPASQTPASN121QPKRPPAAPE131NTPLVPSGVK141SWAQASVTHG
151-200151AHGDGGRASS161LLSRFSREEF171PTLQAAGDQD181KAAKERESAE191QSSGPGPSLR
201-250201PQNSTTWRDG211GGRGPDELEG221PDSKLHHGHD231PRGGLQPSGP241PQFPPYRGMM
251-300251PPFMYPPYLP261FPPPYGPQGP271YRYPTPDGPS281RFPRVAGPRG291SGPPMRLVEP
301-350301VGRPSILKED311NLKEFDQLDQ321ENDDGWAGAH331EEVDYTEKLK341FSDEEDGRDS
351-400351DEEGAEGHRD361SQSASGEERP371PEADGKKGNS381PNSEPPTPKT391AWAETSRPPE
401-450401TEPGPPAPKP411PLPPPHRGPA421GNWGPPGDYP431DRGGPPCKPP441APEDEDEAWR
451-500451QRRKQSSSEI461SLAVERARRR471REEEERRMQE481ERRAACAEKL491KRLDEKFGAP
501-550501DKRLKAEPAA511PPAAPSTPAP521PPAVPKELPA531PPAPPPASAP541TPETEPEEPA
551-600551QAPPAQSTPT561PGVAAAPTLV571SGGGSTSSTS581SGSFEASPVE591PQLPSKEGPE
601-650601PPEEVPPPTT611PPVPKVEPKG621DGIGPTRQPP631SQGLGYPKYQ641KSLPPRFQRQ
651-700651QQEQLLKQQQ661QHQWQQHQQG671SAPPTPVPPS681PPQPVTLGAV691PAPQAPPPPP
701-750701KALYPGALGR711PPPMPPMNFD721PRWMMIPPYV731DPRLLQGRPP741LDFYPPGVHP
751-800751SGLVPRERSD761SGGSSSEPFD771RHAPAMLRER781GTPPVDPKLA791WVGDVFTATP
801-850801AEPRPLTSPL811RQAADEDDKG821MRSETPPVPP831PPPYLASYPG841FPENGAPGPP
851-900851ISRFPLEEPG861PRPLPWPPGS871DEVAKIQTPP881PKKEPPKEET891AQLTGPEAGR
901-950901KPARGVGSGG911QGPPPPRRES921RTETRWGPRP931GSSRRGIPPE941EPGAPPRRAG
951-1000951PIKKPPPPTK961VEELPPKPLE971QGDETPKPPK981PDPLKITKGK991LGGPKETPPN
1001-10501001GNLSPAPRLR1011RDYSYERVGP1021TSCRGRGRGE1031YFARGRGFRG1041TYGGRGRGAR
1051-11001051SREFRSYREF1061RGDDGRGGGT1071GGPNHPPAPR1081GRTASETRSE1091GSEYEEIPKR
1101-11501101RRQRGSETGS1111ETHESDLAPS1121DKEAPTPKEG1131TLTQVPLAPP1141PPGAPPSPAP
1151-12001151ARFTARGGRV1161FTPRGVPSRR1171GRGGGRPPPQ1181VCPGWSPPAK1191SLAPKKPPTG
1201-12501201PLPPSKEPLK1211EKLIPGPLSP1221VARGGSNGGS1231NVGMEDGERP1241RRRRHGRAQQ
1251-13001251QDKPPRFRRL1261KQERENAARG1271SEGKPSLTLP1281ASAPGPEEAL1291TTVTVAPAPR
1301-13501301RAAAKSPDLS1311NQNSDQANEE1321WETASESSDF1331TSERRGDKEA1341PPPVLLTPKA
1351-14001351VGTPGGGGGG1361AVPGISAMSR1371GDLSQRAKDL1381SKRSFSSQRP1391GMERQNRRPG
1401-14501401PGGKAGSSGS1411SSGGGGGGPG1421GRTGPGRGDK1431RSWPSPKNRS1441RPPEERPPGL
1451-15001451PLPPPPPSSS1461AVFRLDQVIH1471SNPAGIQQAL1481AQLSSRQGSV1491TAPGGHPRHK
1501-15501501PGLPQAPQGP1511SPRPPTRYEP1521QRVNSGLSSD1531PHFEEPGPMV1541RGVGGTPRDS
1551-16001551AGVSPFPPKR1561RERPPRKPEL1571LQEESLPPPH1581SSGFLGSKPE1591GPGPQAESRD
1601-16501601TGTEALTPHI1611WNRLHTATSR1621KSYRPSSMEP1631WMEPLSPFED1641VAGTEMSQSD
1651-17001651SGVDLSGDSQ1661VSSGPCSQRS1671SPDGGLKGAA1681EGPPKRPGGS1691SPLNAVPCEG
1701-17501701PPGSEPPRRP1711PPAPHDGDRK1721ELPREQPLPP1731GPIGTERSQR1741TDRGTEPGPI
1751-18001751RPSHRPGPPV1761QFGTSDKDSD1771LRLVVGDSLK1781AEKELTASVT1791EAIPVSRDWE
1801-18501801LLPSAAASAE1811PQSKNLDSGH1821CVPEPSSSGQ1831RLYPEVFYGS1841AGPSSSQISG
1851-19001851GAMDSQLHPN1861SGGFRPGTPS1871LHPYRSQPLY1881LPPGPAPPSA1891LLSGLALKGQ
1901-19501901FLDFSTMQAT1911ELGKLPAGGV1921LYPPPSFLYS1931PAFCPSPLPD1941TSLLQVRQDL
1951-20001951PSPSDFYSTP1961LQPGGQSGFL1971PSGAPAQQML1981LPMVDSQLPV1991VNFGSLPPAP
2001-20502001PPAPPPLSLL2011PVGPALQPPS2021LAVRPPPAPA2031TRVLPSPARP2041FPASLGRAEL
2051-21002051HPVELKPFQD2061YQKLSSNLGG2071PGSSRTPPTG2081RSFSGLNSRL2091KATPSTYSGV
2101-21502101FRTQRVDLYQ2111QASPPDALRW2121IPKPWERTGP2131PPREGPSRRA2141EEPGSRGDKE
2151-21572151PGLPPPR
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
437 - - -
Deep-Palm: 0.39
486 SWISSPALM DBPTM CYSMODDB - - -
GPS-Palm: 0.89
Deep-Palm: 0.98
1023 - - -
GPS-Palm: 0.83
Deep-Palm: 0.81
1182 - - -
GPS-Palm: 0.76
Deep-Palm: 0.95
1666 - - -
Deep-Palm: 0.96
1698 - - -
Deep-Palm: 0.92
1821 - - -
Deep-Palm: 0.79
1934 - - -
Deep-Palm: 0.94
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
482 R → C 0.002288 SNP Missense Mutation STAD
482 R → C 0.005618 SNP Missense Mutation PAAD
486 C → W 0.002033 SNP Missense Mutation THCA
486 C → C 0.001887 SNP Silent UCEC
516 S → C 0.002033 SNP Missense Mutation THCA
627 R → C 0.002506 SNP Missense Mutation COAD
737 G → C 0.001764 SNP Missense Mutation LUAD
758 R → C 0.001887 SNP Missense Mutation UCEC
904 R → C 0.002294 SNP Missense Mutation OV
934 R → C 0.002288 SNP Missense Mutation STAD
934 R → C 0.003774 SNP Missense Mutation UCEC
1152 R → C 0.002288 SNP Missense Mutation STAD
1464 R → C 0.002506 SNP Missense Mutation COAD
1475 G → C 0.002294 SNP Missense Mutation OV
1560 R → C 0.001887 SNP Missense Mutation UCEC
1602 G → C 0.001887 SNP Missense Mutation UCEC
1666 C → C 0.001887 SNP Silent UCEC
1926 S → C 0.002427 SNP Missense Mutation BLCA
1947 R → C 0.002288 SNP Missense Mutation STAD
2089 R → C 0.001887 SNP Missense Mutation UCEC
2119 R → C 0.002288 SNP Missense Mutation STAD
2157 R → C 0.002288 SNP Missense Mutation STAD