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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P48758 Cbr1 Carbonyl reductase [NADPH] 1 (EC … Mus musculus (Mouse) 277 aa

Protein Details: P48758 (Cbr1)

Protein Information
AccessionP48758
Protein NamesCarbonyl reductase [NADPH] 1 (EC 1.1.1.184) (15-hydroxyprostaglandin dehydrogenase [NADP(+)]) (EC 1.1.1.196, EC 1.1.1.197) (20-beta-hydroxysteroid dehydrogenase) (Alcohol dehydrogenase [NAD(P)+] CBR1) (EC 1.1.1.71) (NADPH-dependent carbonyl reductase 1) (Prostaglandin 9-ketoreductase) (PG-9-KR) (Prostaglandin-E(2) 9-reductase) (EC 1.1.1.189)
Gene SymbolCbr1
OrganismMus musculus (Mouse)
Length277 aa
IsoformsNo isoforms
Related PMIDs 28526873 34200797 35358180 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MSSSRPVALV11TGANKGIGFA21ITRDLCRKFS31GDVVLAARDE41ERGQTAVQKL
51-10051QAEGLSPRFH61QLDIDNPQSI71RALRDFLLKE81YGGLDVLVNN91AGIAFKVNDD
101-150101TPFHIQAEVT111MKTNFFGTRD121VCKELLPLIK131PQGRVVNVSS141MVSLRALKNC
151-200151RLELQQKFRS161ETITEEELVG171LMNKFVEDTK181KGVHAEEGWP191NSAYGVTKIG
201-250201VTVLSRILAR211KLNEQRRGDK221ILLNACCPGW231VRTDMAGPKA241TKSPEEGAET
251-277251PVYLALLPPD261AEGPHGQFVQ271DKKVEPW
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
26 CARBONYL REDUCTASE 1-RELATED NAD(P)-binding domain superfamily Short-chain dehydrogenase/reductase SDR - -
GPS-Palm: 0.87
Deep-Palm: 0.97
122 SWISSPALM DBPTM CYSMODDB -
liver (26165157)
-
GPS-Palm: 0.89
Deep-Palm: 0.98
150 - - -
GPS-Palm: 0.93
Deep-Palm: 0.88
226 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
Brain (34200797)
-
GPS-Palm: 0.96
Deep-Palm: 0.94
227 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
Brain (34200797)
-
GPS-Palm: 0.95
Deep-Palm: 0.93
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
4
Liver
Specificity: 0.571
4/4 (100.0%)
3
Brain
Specificity: 0.429
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine