Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P48776 Tdo2 Tryptophan 2,3-dioxygenase (TDO) (EC 1.13.11.11) … Mus musculus (Mouse) 406 aa

Protein Details: P48776 (Tdo2)

Protein Information
AccessionP48776
Protein NamesTryptophan 2,3-dioxygenase (TDO) (EC 1.13.11.11) (Tryptamin 2,3-dioxygenase) (Tryptophan oxygenase) (TO) (TRPO) (Tryptophan pyrrolase) (Tryptophanase)
Gene SymbolTdo2
OrganismMus musculus (Mouse)
Length406 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MSGCPFAGNS11VGYTLKNVSM21EDNEEDRAQT31GVNRASKGGL41IYGNYLQLEK
51-10051ILNAQELQSE61VKGNKIHDEH71LFIITHQAYE81LWFKQILWEL91DSVREIFQNG
101-150101HVRDERNMLK111VIARMHRVVV121IFKLLVQQFS131VLETMTALDF141NDFREYLSPA
151-200151SGFQSLQFRL161LENKIGVLQS171LRVPYNRKHY181RDNFGGDYNE191LLLKSEQEQT
201-250201LLQLVEAWLE211RTPGLEPNGF221NFWGKFEKNI231LKGLEEEFLR241IQAKTDSEEK
251-300251EEQMAEFRKQ261KEVLLCLFDE271KRHDYLLSKG281ERRLSYRALQ291GALMIYFYRE
301-350301EPRFQVPFQL311LTSLMDIDTL321MTKWRYNHVC331MVHRMLGTKA341GTGGSSGYHY
351-400351LRSTVSDRYK361VFVDLFNLST371YLVPRHWVPK381MNPIIHKFLY391TAEYSDSSYF
401-406401SSDESD
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
4 - - -
GPS-Palm: 0.95
Deep-Palm: 0.02
266 SWISSPALM DBPTM CYSMODDB Tryptophan 2 3-dioxygenase
Liver (28526873)
-
GPS-Palm: 0.94
Deep-Palm: 0.97
330 - - -
Deep-Palm: 0.29
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
5
Liver
Specificity: 1.000
5/5 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine