Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P48960-2 | ADGRE5 | Adhesion G protein-coupled receptor E5 … | Homo sapiens (Human) | 742 aa |
Protein Details: P48960-2 (ADGRE5)
Protein Information
| Accession | P48960-2 |
|---|---|
| Protein Names | Adhesion G protein-coupled receptor E5 (Leukocyte antigen CD97) (CD antigen CD97) [Cleaved into: Adhesion G protein-coupled receptor E5 subunit alpha; Adhesion G protein-coupled receptor E5 subunit beta] |
| Gene Symbol | ADGRE5 |
| Organism | Homo sapiens (Human) |
| Length | 742 aa |
| Isoforms | |
| Related PMIDs | 26111759 29575903 31251020 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGGRVFLAFC11VWLTLPGAET21QDSRGCARWC31PQNSSCVNAT41ACRCNPGFSS
51-10051FSEIITTPTE61TCDDINECAT71PSKVSCGKFS81DCWNTEGSYD91CVCSPGYEPV
101-150101SGAKTFKNES111ENTCQDVDEC121SSGQHQCDSS131TVCFNTVGSY141SCRCRPGWKP
151-200151RHGIPNNQKD161TVCEDMTFST171WTPPPGVHSQ181TLSRFFDKVQ191DLGRDSKTSS
201-250201AEVTIQNVIK211LVDELMEAPG221DVEALAPPVR231HLIATQLLSN241LEDIMRILAK
251-300251SLPKGPFTYI261SPSNTELTLM271IQERGDKNVT281MGQSSARMKL291NWAVAAGAED
301-350301PGPAVAGILS311IQNMTTLLAN321ASLNLHSKKQ331AELEEIYESS341IRGVQLRRLS
351-400351AVNSIFLSHN361NTKELNSPIL371FAFSHLESSD381GEAGRDPPAK391DVMPGPRQEL
401-450401LCAFWKSDSD411RGGHWATEGC421QVLGSKNGST431TCQCSHLSSF441AILMAHYDVE
451-500451DWKLTLITRV461GLALSLFCLL471LCILTFLLVR481PIQGSRTTIH491LHLCICLFVG
501-550501STIFLAGIEN511EGGQVGLRCR521LVAGLLHYCF531LAAFCWMSLE541GLELYFLVVR
551-600551VFQGQGLSTR561WLCLIGYGVP571LLIVGVSAAI581YSKGYGRPRY591CWLDFEQGFL
601-650601WSFLGPVTFI611ILCNAVIFVT621TVWKLTQKFS631EINPDMKKLK641KARALTITAI
651-700651AQLFLLGCTW661VFGLFIFDDR671SLVLTYVFTI681LNCLQGAFLY691LLHCLLNKKV
701-742701REEYRKWACL711VAGGSKYSEF721TSTTSGTGHN731QTRALRASES741GI
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 10 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.09
|
|
| 26 | Laminin | - | - |
Deep-Palm: 0.25
|
|
| 30 | Laminin | - | - |
Deep-Palm: 0.07
|
|
| 36 | Laminin | - | - |
Deep-Palm: 0.05
|
|
| 42 | Laminin | - | - |
Deep-Palm: 0.04
|
|
| 44 | Laminin | - | - |
Deep-Palm: 0.04
|
|
| 62 | - | - | - |
Deep-Palm: 0.08
|
|
| 68 | - | - | - |
Deep-Palm: 0.03
|
|
| 76 | - | - | - |
Deep-Palm: 0.03
|
|
| 82 | - | - | - |
Deep-Palm: 0.04
|
|
| 91 | - | - | - |
Deep-Palm: 0.08
|
|
| 93 | - | - | - |
Deep-Palm: 0.07
|
|
| 114 | - | - | - |
Deep-Palm: 0.05
|
|
| 120 | - | - | - |
Deep-Palm: 0.02
|
|
| 127 | - | - | - |
Deep-Palm: 0.03
|
|
| 133 | - | - | - |
Deep-Palm: 0.04
|
|
| 142 | - | - | - |
Deep-Palm: 0.06
|
|
| 144 | - | - | - |
Deep-Palm: 0.04
|
|
| 158 | - | - | - |
Deep-Palm: 0.02
|
|
| 164 | - | - | - |
Deep-Palm: 0.02
|
|
| 171 | - | - | - |
Deep-Palm: 0.01
|
|
| 177 | - | - | - |
Deep-Palm: 0.01
|
|
| 186 | - | - | - |
Deep-Palm: 0.02
|
|
| 188 | - | - | - |
Deep-Palm: 0.02
|
|
| 207 | - | - | - |
Deep-Palm: 0.01
|
|
| 213 | - | - | - |
Deep-Palm: 0.01
|
|
| 220 | - | - | - |
Deep-Palm: 0.01
|
|
| 226 | - | - | - |
Deep-Palm: 0.02
|
|
| 235 | - | - | - |
Deep-Palm: 0.03
|
|
| 237 | - | - | - |
Deep-Palm: 0.03
|
|
| 256 | - | - | - |
Deep-Palm: 0.07
|
|
| 402 | - | - | - |
GPS-Palm: 0.72
|
|
| 420 | - | - | - |
GPS-Palm: 0.75
|
|
| 468 | - | - | - |
GPS-Palm: 0.70
|
|
| 472 | - | - | - |
GPS-Palm: 0.68
|
|
| 495 | - | - | - |
Deep-Palm: 0.84
|
|
| 513 | - | - | - |
Deep-Palm: 0.18
|
|
| 525 | - | - | - |
Deep-Palm: 0.09
|
|
| 527 | - | - | - |
Deep-Palm: 0.08
|
|
| 561 | - | - | - |
Deep-Palm: 0.98
|
|
| 565 | - | - | - |
Deep-Palm: 0.97
|
|
| 587 | - | - | - |
Deep-Palm: 0.23
|
|
| 589 | - | - | - |
Deep-Palm: 0.17
|
|
| 612 | - | - | - |
Deep-Palm: 0.95
|
|
| 622 | - | - | - |
Deep-Palm: 0.54
|
|
| 628 | - | - | - |
Deep-Palm: 0.23
|
|
| 656 | - | - | - |
Deep-Palm: 0.97
|
|
| 683 | - | - | - |
GPS-Palm: 0.68
|
|
| 684 | - | - | - |
Deep-Palm: 0.33
|
|
| 694 | - | - | - |
GPS-Palm: 0.88
|
|
| 706 | - | - | - |
Deep-Palm: 0.25
|
|
| 709 | - | - | - |
GPS-Palm: 0.92
|
|
| 751 | - | - | - |
Deep-Palm: 0.89
|
|
| 776 | - | - | - |
Deep-Palm: 0.67
|
|
| 787 | - | - | - |
Deep-Palm: 0.82
|
|
| 802 | - | - | - |
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
2
LNCaP
Specificity: 0.400
2/2 (100.0%)
2
Jurkat T cell
Specificity: 0.400
2/2 (100.0%)
1
HeLa cell
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 43 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 88 | S → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 91 | C → C | 0.002506 | SNP | Silent | COAD |
| 127 | C → R | 0.001764 | SNP | Missense Mutation | LUAD |
| 133 | C → C | 0.001969 | SNP | Silent | HNSC |
| 144 | C → Y | 0.001014 | SNP | Missense Mutation | BRCA |
| 173 | S → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 380 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 513 | C → R | 0.001764 | SNP | Missense Mutation | LUAD |
| 527 | C → Y | 0.010870 | SNP | Missense Mutation | ACC |
| 579 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 612 | C → F | 0.003559 | SNP | Missense Mutation | KIRP |
| 706 | C → R | 0.002506 | SNP | Missense Mutation | COAD |
| 750 | G → C | 0.002294 | SNP | Missense Mutation | OV |
| 177* | C → ? | 0.002545 | SNP | Nonsense Mutation | GBM |