Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P49006 | MARCKSL1 | MARCKS-related protein (MARCKS-like protein 1) … | Homo sapiens (Human) | 195 aa |
Protein Details: P49006 (MARCKSL1)
Protein Information
| Accession | P49006 |
|---|---|
| Protein Names | MARCKS-related protein (MARCKS-like protein 1) (Macrophage myristoylated alanine-rich C kinase substrate) (Mac-MARCKS) (MacMARCKS) |
| Gene Symbol | MARCKSL1 |
| Organism | Homo sapiens (Human) |
| Length | 195 aa |
| Isoforms | No isoforms |
| Related PMIDs | 25914232 29733200 31251020 32944167 36430497 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGSQSSKAPR11GDVTAEEAAG21ASPAKANGQE31NGHVKSNGDL41SPKGEGESPP
51-10051VNGTDEAAGA61TGDAIEPAPP71SQGAEAKGEV81PPKETPKKKK91KFSFKKPFKL
101-150101SGLSFKRNRK111EGGGDSSASS121PTEEEQEQGE131IGACSDEGTA141QEGKAAATPE
151-195151SQEPQAKGAE161ASAASEEEAG171PQATEPSTPS181GPESGPTPAS191AEQNE
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 134 | - | - | - |
Deep-Palm: 0.88
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.364
4
PC3
Specificity: 0.364
4/4 (100.0%)
2
LNCaP
Specificity: 0.182
2/2 (100.0%)
2
CEM 174 cell
Specificity: 0.182
2/2 (100.0%)
1
HAP1 cell
Specificity: 0.091
1/1 (100.0%)
1
293T cell
Specificity: 0.091
1/1 (100.0%)
1
cerebral cortex
Specificity: 0.091
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 119 | S → C | 0.001014 | SNP | Missense Mutation | BRCA |