Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P49189-2 | ALDH9A1 | 4-trimethylaminobutyraldehyde dehydrogenase (TMABA-DH) (TMABALDH) (EC … | Homo sapiens (Human) | 424 aa |
Protein Details: P49189-2 (ALDH9A1)
Protein Information
| Accession | P49189-2 |
|---|---|
| Protein Names | 4-trimethylaminobutyraldehyde dehydrogenase (TMABA-DH) (TMABALDH) (EC 1.2.1.47) (Aldehyde dehydrogenase E3 isozyme) (Aldehyde dehydrogenase family 9 member A1) (EC 1.2.1.3) (Formaldehyde dehydrogenase) (EC 1.2.1.46) (Gamma-aminobutyraldehyde dehydrogenase) (EC 1.2.1.19) (R-aminobutyraldehyde dehydrogenase) [Cleaved into: 4-trimethylaminobutyraldehyde dehydrogenase, N-terminally processed] |
| Gene Symbol | ALDH9A1 |
| Organism | Homo sapiens (Human) |
| Length | 424 aa |
| Isoforms | |
| Related PMIDs | 31251020 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MERCRILLEA11ARIIREREDE21IATMECINNG31KSIFEARLDI41DISWQCLEYY
51-10051AGLAASMAGE61HIQLPGGSFG71YTRREPLGVC81VGIGAWNYPF91QIASWKSAPA
101-150101LACGNAMVFK111PSPFTPVSAL121LLAEIYSEAG131VPPGLFNVVQ141GGAATGQFLC
151-200151QHPDVAKVSF161TGSVPTGMKI171MEMSAKGIKP181VTLELGGKSP191LIIFSDCDMN
201-250201NAVKGALMAN211FLTQGQVCCN221GTRVFVQKEI231LDKFTEEVVK241QTQRIKIGDP
251-300251LLEDTRMGPL261INRPHLERVL271GFVKVAKEQG281AKVLCGGDIY291VPEDPKLKDG
301-350301YYMRPCVLTN311CRDDMTCVKE321EIFGPVMSIL331SFDTEAEVLE341RANDTTFGLA
351-400351AGVFTRDIQR361AHRVVAELQA371GTCFINNYNV381SPVELPFGGY391KKSGFGRENG
401-424401RVTIEYYSQL411KTVCVEMGDV421ESAF
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 45 | - | - | - |
Deep-Palm: 0.98
|
|
| 74 | - | - | - |
Deep-Palm: 0.95
|
|
| 96 | - | - | - |
Deep-Palm: 0.63
|
|
| 116 | - | - | - |
Deep-Palm: 0.76
|
|
| 150 | - | - | - |
Deep-Palm: 0.91
|
|
| 173 | - | - | - |
Deep-Palm: 0.75
|
|
| 220 | - | - | - |
Deep-Palm: 0.95
|
|
| 267 | - | - | - |
Deep-Palm: 0.94
|
|
| 288 | - | - | - |
Deep-Palm: 0.91
|
|
| 289 | - | - | - |
Deep-Palm: 0.87
|
|
| 355 | - | - | - |
Deep-Palm: 0.98
|
|
| 376 | - | - | - |
Deep-Palm: 0.19
|
|
| 381 | - | - | - |
Deep-Palm: 0.73
|
|
| 387 | - | - | - |
Deep-Palm: 0.68
|
|
| 443 | - | - | - |
Deep-Palm: 0.97
|
|
| 484 | - | - | - |
Deep-Palm: 0.05
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
4
cerebral cortex
Specificity: 0.400
4/4 (100.0%)
3
LNCaP
Specificity: 0.300
3/3 (100.0%)
3
PC3
Specificity: 0.300
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 15 | R → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 131 | R → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 165 | Y → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 220 | Y → C | 0.012195 | SNP | Missense Mutation | MESO |
| 495 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| ? | ? → ? | 0.002033 | SNP | Nonstop Mutation | LUSC |