Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P49429 Hpd 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4-hydroxyphenylpyruvic … Mus musculus (Mouse) 393 aa

Protein Details: P49429 (Hpd)

Protein Information
AccessionP49429
Protein Names4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4-hydroxyphenylpyruvic acid oxidase) (4HPPD) (HPD) (HPPDase) (F Alloantigen) (F protein)
Gene SymbolHpd
OrganismMus musculus (Mouse)
Length393 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MTTYNNKGPK11PERGRFLHFH21SVTFWVGNAK31QAASFYCNKM41GFEPLAYRGL
51-10051ETGSREVVSH61VIKQGKIVFV71LCSALNPWNK81EMGDHLVKHG91DGVKDIAFEV
101-150101EDCDHIVQKA111RERGAKIVRE121PWVEQDKFGK131VKFAVLQTYG141DTTHTLVEKI
151-200151NYTGRFLPGF161EAPTYKDTLL171PKLPRCNLEI181IDHIVGNQPD191QEMQSASEWY
201-250201LKNLQFHRFW211SVDDTQVHTE221YSSLRSIVVT231NYEESIKMPI241NEPAPGRKKS
251-300251QIQEYVDYNG261GAGVQHIALK271TEDIITAIRH281LRERGTEFLA291APSSYYKLLR
301-350301ENLKSAKIQV311KESMDVLEEL321HILVDYDEKG331YLLQIFTKPM341QDRPTLFLEV
351-393351IQRHNHQGFG361AGNFNSLFKA371FEEEQALRGN381LTDLEPNGVR391SGM
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
37 SWISSPALM DBPTM CYSMODDB 4-hydroxyphenylpyruvate dioxygenase Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Vicinal oxygen chelate (VOC) domain
Liver (28526873)
-
GPS-Palm: 0.82
Deep-Palm: 0.93
72 SWISSPALM DBPTM CYSMODDB -
liver (26165157)
-
GPS-Palm: 0.92
Deep-Palm: 0.81
103 - - -
GPS-Palm: 0.70
Deep-Palm: 0.93
176 - - -
Deep-Palm: 0.74
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
6
Liver
Specificity: 1.000
6/6 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine