Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P49588-2 AARS1 Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) … Homo sapiens (Human) 992 aa

Protein Details: P49588-2 (AARS1)

Protein Information
AccessionP49588-2
Protein NamesAlanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS) (Protein lactyltransferase AARS1) (EC 6.-.-.-) (Renal carcinoma antigen NY-REN-42)
Gene SymbolAARS1
OrganismHomo sapiens (Human)
Length992 aa
Isoforms
Related PMIDs 26876311 31251020 32944167 36430497
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MDSTLTASEI11RQRFIDFFKR21NEHTYVHSSA31TIPLDDPTLL41FANAGMNQFK
51-10051PIFLNTIDPS61HPMAKLSRAA71NTQKCIRAGG81KHNDLDDVGK91DVYHHTFFEM
101-150101LGSWSFGDYF111KELACKMALE121LLTQEFGIPI131ERLYVTYFGG141DEAAGLEADL
151-200151ECKQIWQNLG161TYLYSFVRLD171DTKILPGNMK181DNFWEMGDTG191PCGPCSEIHY
201-250201DRIGGRDAAH211LVNQDDPNVL221EIWNLVFIQY231NREADGILKP241LPKKSIDTGM
251-300251GLERLVSVLQ261NKMSNYDTDL271FVPYFEAIQK281GTGARPYTGK291VGAEDADGID
301-350301MAYRVLADHA311RTITVALADG321GRPDNTGRGY331VLRRILRRAV341RYAHEKLNAS
351-400351RGFFATLVDV361VVQSLGDAFP371ELKKDPDMVK381DIINEEEVQF391LKTLSRGRRI
401-450401LDRKIQSLGD411SKTIPGDTAW421LLYDTYGFPV431DLTGLIAEEK441GLVVDMDGFE
451-500451EERKLAQLKS461QGKGAGGEDL471IMLDIYAIEE481LRARGLEVTD491DSPKYNYHLD
501-550501SSGSYVFENT511VATVMALRRE521KMFVEEVSTG531QECGVVLDKT541CFYAEQGGQI
551-600551YDEGYLVKVD561DSSEDKTEFT571VKNAQVRGGY581VLHIGTIYGD591LKVGDQVWLF
601-650601IDEPRRRPIM611SNHTATHILN621FALRSVLGEA631DQKGSLVAPD641RLRFDFTAKG
651-700651AMSTQQIKKA661EEIANEMIEA671AKAVYTQDCP681LAAAKAIQGL691RAVFDETYPD
701-750701PVRVVSIGVP711VSELLDDPSG721PAGSLTSVEF731CGGTHLRNSS741HAGAFVIVTE
751-800751EAIAKGIRRI761VAVTGAEAQK771ALRKAESLKK781CLSVMEAKVK791AQTAPNKDVQ
801-850801REIADLGEAL811ATAVIPQWQK821DELRETLKSL831KKVMDDLDRA841SKADVQKRVL
851-900851EKTKQFIDSN861PNQPLVILEM871ESGASAKATQ881GPGSPPLGLI891SSLALNEALK
901-950901LFKMHSPQTS911AMLFTVDNEA921GKITCLCQVP931QNAANRGLKA941SEWVQQVSGL
951-992951MDGKGGGKDV961SAQATGKNVG971CLQEALQLAT981SFAQLRLGDV991KN
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
75 - - -
Deep-Palm: 0.92
115 - - -
Deep-Palm: 0.94
152 - - -
Deep-Palm: 0.94
184 - - -
Deep-Palm: 0.08
187 - - -
Deep-Palm: 0.09
525 - - -
Deep-Palm: 0.73
533 - - -
Deep-Palm: 0.63
671 - - -
Deep-Palm: 0.97
723 - - -
Deep-Palm: 0.96
773 - - -
Deep-Palm: 0.98
781 - - -
GPS-Palm: 0.94
901 - - -
Deep-Palm: 0.88
903 - - -
Deep-Palm: 0.87
947 - - -
Deep-Palm: 0.97
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.333
4
PC3
Specificity: 0.333
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.333
4/4 (100.0%)
3
LNCaP
Specificity: 0.250
3/3 (100.0%)
1
frontal cortex
Specificity: 0.083
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.