Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P49698 Hnf4a Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) … Mus musculus (Mouse) 474 aa

Protein Details: P49698 (Hnf4a)

Protein Information
AccessionP49698
Protein NamesHepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Nuclear receptor subfamily 2 group A member 1) (Transcription factor 14) (TCF-14) (Transcription factor HNF-4)
Gene SymbolHnf4a
OrganismMus musculus (Mouse)
Length474 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MRLSKTLAGM11DMADYSAALD21PAYTTLEFEN31VQVLTMGNDT41SPSEGANLNS
51-10051SNSLGVSALC61AICGDRATGK71HYGASSCDGC81KGFFRRSVRK91NHMYSCRFSR
101-150101QCVVDKDKRN111QCRYCRLKKC121FRAGMKKEAV131QNERDRISTR141RSSYEDSSLP
151-200151SINALLQAEV161LSQQITSPIS171GINGDIRAKK181IANITDVCES191MKEQLLVLVE
201-250201WAKYIPAFCE211LLLDDQVALL221RAHAGEHLLL231GATKRSMVFK241DVLLLGNDYI
251-300251VPRHCPELAE261MSRVSIRILD271ELVLPFQELQ281IDDNEYACLK291AIIFFDPDAK
301-350301GLSDPGKIKR311LRSQVQVSLE321DYINDRQYDS331RGRFGELLLL341LPTLQSITWQ
351-400351MIEQIQFIKL361FGMAKIDNLL371QEMLLGGSAS381DAPHTHHPLH391PHLMQEHMGT
401-450401NVIVANTMPS411HLSNGQMCEW421PRPRGQAATP431ETPQPSPPSG441SGSESYKLLP
451-474451GAITTIVKPP461SAIPQPTITK471QEAI
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
60 - - -
GPS-Palm: 0.81
Deep-Palm: 0.84
63 - - -
GPS-Palm: 0.86
Deep-Palm: 0.78
77 - - -
GPS-Palm: 0.83
Deep-Palm: 0.36
80 - - -
GPS-Palm: 0.82
Deep-Palm: 0.21
96 - - -
GPS-Palm: 0.76
Deep-Palm: 0.13
102 - - -
Deep-Palm: 0.05
112 - - -
GPS-Palm: 0.72
Deep-Palm: 0.19
115 - - -
GPS-Palm: 0.86
Deep-Palm: 0.50
120 - - -
GPS-Palm: 0.76
Deep-Palm: 0.49
188 SWISSPALM DBPTM CYSMODDB Ligand-binding domain of nuclear hormone receptor
Liver (28526873)
-
GPS-Palm: 0.91
Deep-Palm: 0.95
209 - - -
Deep-Palm: 0.93
255 - - -
Deep-Palm: 0.96
288 - - -
GPS-Palm: 0.69
Deep-Palm: 0.92
418 - - -
Deep-Palm: 0.34
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
5
Liver
Specificity: 1.000
5/5 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine