Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P50171-2 | Hsd17b8 | (3R)-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12) (17-beta-hydroxysteroid … | Mus musculus (Mouse) | 274 aa |
Protein Details: P50171-2 (Hsd17b8)
Protein Information
| Accession | P50171-2 |
|---|---|
| Protein Names | (3R)-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12) (17-beta-hydroxysteroid dehydrogenase 8) (17-beta-HSD 8) (3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit) (KAR alpha subunit) (3-oxoacyl-[acyl-carrier-protein] reductase) (Estradiol 17-beta-dehydrogenase 8) (EC 1.1.1.62) (Protein Ke6) (Ke-6) (Testosterone 17-beta-dehydrogenase 8) (EC 1.1.1.239) |
| Gene Symbol | Hsd17b8 |
| Organism | Mus musculus (Mouse) |
| Length | 274 aa |
| Isoforms | |
| Related PMIDs | 35477839 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MASQLRLRSA11LALVTGAGSG21IGRAISVRLA31AEGAAVAACD41LDGAAAQDTV
51-10051RLLGSPGSED61GAPRGKHAAF71QADVSQGPAA81RRLLEEVQAC91FSRPPSVVVS
101-150101CAGITRDEFL111LHMSEEDWDR121VIAVNLKGTF131LVTQAAAQAL141VSSGGRGSII
151-200151NISSIIGKVG161NIGQTNYASS171KAGVIGLTQT181AARELGRHGI191RCNSVLPGFI
201-250201ATPMTQKMPE211KVKDKVTAMI221PLGHMGDPED231VADVVAFLAS241EDSGYITGAS
251-274251VEVSGMRPSW261GGGQENRTQV271VMRK
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 39 | NAD(P)-binding domain superfamily Short-chain dehydrogenase/reductase SDR | - |
Brain
(35358180)
|
Deep-Palm: 0.98
|
|
| 90 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.98
|
|
| 101 | - | - | - |
Deep-Palm: 0.95
|
|
| 192 | - | - | - |
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Testis
Specificity: 0.333
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Brain tissue (Mass)
Specificity: 0.667
4/56 (7.1%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.