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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P50172 Hsd11b1 11-beta-hydroxysteroid dehydrogenase 1 (11-DH) (11-beta-HSD1) … Mus musculus (Mouse) 292 aa

Protein Details: P50172 (Hsd11b1)

Protein Information
AccessionP50172
Protein Names11-beta-hydroxysteroid dehydrogenase 1 (11-DH) (11-beta-HSD1) (EC 1.1.1.146) (11-beta-hydroxysteroid dehydrogenase/microsomal carbonyl reductase) (11-beta-HSD1A/MCR) (11beta-HSD1A) (7-oxosteroid reductase) (EC 1.1.1.201) (Corticosteroid 11-beta-dehydrogenase isozyme 1) (liver-type 11-beta-HSD)
Gene SymbolHsd11b1
OrganismMus musculus (Mouse)
Length292 aa
IsoformsNo isoforms
Related PMIDs 28526873 29660268 34884899 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAVMKNYLLP11ILVLFLAYYY21YSTNEEFRPE31MLQGKKVIVT41GASKGIGREM
51-10051AYHLSKMGAH61VVLTARSEEG71LQKVVSRCLE81LGAASAHYIA91GTMEDMTFAE
101-150101QFIVKAGKLM111GGLDMLILNH121ITQTSLSLFH131DDIHSVRRVM141EVNFLSYVVM
151-200151STAALPMLKQ161SNGSIAVISS171LAGKMTQPMI181APYSASKFAL191DGFFSTIRTE
201-250201LYITKVNVSI211TLCVLGLIDT221ETAMKEISGI231INAQASPKEE241CALEIIKGTA
251-292251LRKSEVYYDK261SPLTPILLGN271PGRKIMEFFS281LRYYNKDMFV291SN
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
78 - - -
GPS-Palm: 0.67
Deep-Palm: 0.97
213 - - -
GPS-Palm: 0.79
Deep-Palm: 0.76
241 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
-
GPS-Palm: 0.69
Deep-Palm: 0.96
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.857
6
Liver
Specificity: 0.857
6/6 (100.0%)
1
Brain
Specificity: 0.143
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine