Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P50285 Fmo1 Flavin-containing monooxygenase 1 (EC 1.14.13.148) … Mus musculus (Mouse) 532 aa

Protein Details: P50285 (Fmo1)

Protein Information
AccessionP50285
Protein NamesFlavin-containing monooxygenase 1 (EC 1.14.13.148) (EC 1.14.13.8) (Dimethylaniline monooxygenase [N-oxide-forming] 1) (Dimethylaniline oxidase 1) (Hepatic flavin-containing monooxygenase 1) (FMO 1) (Trimethylamine monooxygenase)
Gene SymbolFmo1
OrganismMus musculus (Mouse)
Length532 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899 35477839 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MVKRVAIVGA11GVSGLASIKC21CLEEGLEPTC31FERSSDLGGL41WRFTEHVEEG
51-10051RASLYKSVVS61NSSREMSCYP71DFPFPEDYPN81FVPNSLFLEY91LKLYSTQFNL
101-150101QRCIYFNTKV111CSITKRPDFA121VSGQWEVVTV131TNGKQNSAIF141DAVMVCTGFL
151-200151TNPHLPLDSF161PGILTFKGEY171FHSRQYKHPD181IFKDKRVLVV191GMGNSGTDIA
201-250201VEASHLAKKV211FLSTTGGAWV221ISRVFDSGYP231WDMIFMTRFQ241NMLRNLLPTP
251-300251IVSWLISKKM261NSWFNHVNYG271VAPEDRTQLR281EPVLNDELPG291RIITGKVFIK
301-350301PSIKEVKENS311VVFNNTPKEE321PIDIIVFATG331YTFAFPFLDE341SVVKVEDGQA
351-400351SLYKYIFPAH361LPKPTLAVIG371LIKPLGSMVP381TGETQARWVV391QVLKGATTLP
401-450401PPSVMMEEVN411ERKKNKHSGF421GLCYCKALQT431DYITYIDDLL441TSINAKPDLR
451-500451AMLLTDPRLA461LSIFFGPCTP471YHFRLTGPGK481WEGARKAILT491QWDRTVKVTK
501-532501TRTIQESPSS511FETLLKLFSF521LALLIAVFLI531FL
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
20 FAD/NAD(P)-binding domain superfamily Adrenodoxin reductase family signature Flavin monooxygenase-like Flavin-containing monooxygenases-like - -
GPS-Palm: 0.73
Deep-Palm: 0.93
21 FAD/NAD(P)-binding domain superfamily Adrenodoxin reductase family signature Flavin monooxygenase-like Flavin-containing monooxygenases-like - -
GPS-Palm: 0.76
Deep-Palm: 0.93
30 FAD/NAD(P)-binding domain superfamily Flavin-containing monooxygenases-like Flavin monooxygenase-like - -
Deep-Palm: 0.92
68 - - -
Deep-Palm: 0.29
103 - -
NSC (31772009)
Deep-Palm: 0.36
111 - -
NSC (31772009)
GPS-Palm: 0.85
Deep-Palm: 0.23
146 - - -
Deep-Palm: 0.50
423 SWISSPALM DBPTM CYSMODDB Flavin-binding monooxygenase-like
Liver (28526873)
-
GPS-Palm: 0.71
Deep-Palm: 0.31
425 Flavin-binding monooxygenase-like
Liver (28526873)
-
Deep-Palm: 0.42
468 - - -
GPS-Palm: 0.85
Deep-Palm: 0.96
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
6
Liver
Specificity: 0.750
6/6 (100.0%)
2
Testis
Specificity: 0.250
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine