Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P50431 | Shmt1 | Serine hydroxymethyltransferase, cytosolic (SHMT) (cSHMT) … | Mus musculus (Mouse) | 478 aa |
Protein Details: P50431 (Shmt1)
Protein Information
| Accession | P50431 |
|---|---|
| Protein Names | Serine hydroxymethyltransferase, cytosolic (SHMT) (cSHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase) |
| Gene Symbol | Shmt1 |
| Organism | Mus musculus (Mouse) |
| Length | 478 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 34884899 35477839 37925639 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MADRDATLWA11SHEKMLSQPL21KDSDAEVYSI31IKKESNRQRV41GLELIASENF
51-10051ASRAVLEALG61SCLNNKYSEG71YPGQRYYGGT81EFIDELEMLC91QKRALQAYHL
101-150101DPQCWGVNVQ111PYSGSPANFA121VYTALVEPHG131RIMGLDLPDG141GHLTHGFMTD
151-200151KKKISATSIF161FESMPYKVYP171ETGYINYDQL181EENASLFHPK191LIIAGTSCYS
201-250201RNLDYARLRK211IADDNGAYLM221ADMAHISGLV231AAGVVPSPFE241HCHVVTTTTH
251-300251KTLRGCRAGM261IFYRKGVRSV271DPKTGKETYY281ELESLINSAV291FPGLQGGPHN
301-350301HAIAGVAVAL311KQAMTTEFKI321YQLQVLANCR331ALSDALTELG341YKIVTGGSDN
351-400351HLILMDLRSK361GTDGGRAEKV371LEACSIACNK381NTCPGDKSAL391RPSGLRLGTP
401-450401ALTSRGLLEE411DFQKVAHFIH421RGIELTLQIQ431SHMATKATLK441EFKEKLAGDE
451-478451KIQSAVATLR461EEVENFASNF471SLPGLPDF
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 62 | - | - | - |
GPS-Palm: 0.89
Deep-Palm: 0.97
|
|
| 90 | SWISSPALM DBPTM CYSMODDB | Serine hydroxymethyltransferase |
Liver
(28526873)
| - |
Deep-Palm: 0.59
|
| 104 | - | - | - |
Deep-Palm: 0.38
|
|
| 198 | SWISSPALM DBPTM CYSMODDB | Serine hydroxymethyltransferase |
Liver
(28526873)
| - |
GPS-Palm: 0.93
Deep-Palm: 0.92
|
| 242 | - | - | - |
Deep-Palm: 0.96
|
|
| 256 | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.81
|
|
| 329 | SWISSPALM DBPTM CYSMODDB | Serine hydroxymethyltransferase |
Liver
(28526873)
| - |
GPS-Palm: 0.82
Deep-Palm: 0.95
|
| 374 | SWISSPALM DBPTM CYSMODDB | Serine hydroxymethyltransferase |
Liver
(28526873)
| - |
GPS-Palm: 0.70
Deep-Palm: 0.94
|
| 378 | SWISSPALM DBPTM CYSMODDB | Serine hydroxymethyltransferase |
Liver
(28526873)
| - |
GPS-Palm: 0.76
Deep-Palm: 0.96
|
| 383 | - | - | - |
GPS-Palm: 0.76
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.714
5
Liver
Specificity: 0.714
5/5 (100.0%)
2
Testis
Specificity: 0.286
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.