Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P50431 | Shmt1; Shmt | Serine hydroxymethyltransferase, cytosolic (SHMT) (EC … | Mus musculus (Mouse) | 478 aa |
Protein Details: P50431 (Shmt1)
Protein Information
| Accession | P50431 |
|---|---|
| Protein Names | Serine hydroxymethyltransferase, cytosolic (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase) |
| Gene Symbol | Shmt1; Shmt |
| Organism | Mus musculus (Mouse) |
| Length | 478 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26165157 28526873 31772009 34884899 35477839 37925639 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.704
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
19
Liver tissue
Specificity: 0.704
19/19 (100.0%)
3
Neural Stem Cells
Specificity: 0.111
3/3 (100.0%)
3
Liver membrane
Specificity: 0.111
3/6 (50.0%)
2
Testis
Specificity: 0.074
2/2 (100.0%)
0
Brain tissue
Specificity: 0.000
0/12 (0.0%)
0
Macrophage Raw 264.7
Specificity: 0.000
0/2 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MADRDATLWA11SHEKMLSQPL21KDSDAEVYSI31IKKESNRQRV41GLELIASENF
51-10051ASRAVLEALG61SCLNNKYSEG71YPGQRYYGGT81EFIDELEMLC91QKRALQAYHL
101-150101DPQCWGVNVQ111PYSGSPANFA121VYTALVEPHG131RIMGLDLPDG141GHLTHGFMTD
151-200151KKKISATSIF161FESMPYKVYP171ETGYINYDQL181EENASLFHPK191LIIAGTSCYS
201-250201RNLDYARLRK211IADDNGAYLM221ADMAHISGLV231AAGVVPSPFE241HCHVVTTTTH
251-300251KTLRGCRAGM261IFYRKGVRSV271DPKTGKETYY281ELESLINSAV291FPGLQGGPHN
301-350301HAIAGVAVAL311KQAMTTEFKI321YQLQVLANCR331ALSDALTELG341YKIVTGGSDN
351-400351HLILMDLRSK361GTDGGRAEKV371LEACSIACNK381NTCPGDKSAL391RPSGLRLGTP
401-450401ALTSRGLLEE411DFQKVAHFIH421RGIELTLQIQ431SHMATKATLK441EFKEKLAGDE
451-478451KIQSAVATLR461EEVENFASNF471SLPGLPDF
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 62 | Prediction (High) | - | - |
| 90 | Experimental CYSMODDB SWISSPALM DBPTM | Serine hydroxymethyltransferase | 28526873 |
| 198 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) | Serine hydroxymethyltransferase | 26165157, 28526873 |
| 256 | Prediction (High) | - | - |
| 329 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) | Serine hydroxymethyltransferase | 28526873 |
| 374 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Low) | Serine hydroxymethyltransferase | 28526873 |
| 378 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Low) | Serine hydroxymethyltransferase | 28526873 |
| 383 | Prediction (Low) | - | - |