Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P50895 | BCAM | Basal cell adhesion molecule (Auberger … | Homo sapiens (Human) | 628 aa |
Protein Details: P50895 (BCAM)
Protein Information
| Accession | P50895 |
|---|---|
| Protein Names | Basal cell adhesion molecule (Auberger B antigen) (B-CAM cell surface glycoprotein) (F8/G253 antigen) (Lutheran antigen) (Lutheran blood group glycoprotein) (CD antigen CD239) |
| Gene Symbol | BCAM |
| Organism | Homo sapiens (Human) |
| Length | 628 aa |
| Isoforms | No isoforms |
| Related PMIDs | 24357059 29733200 31251020 33636221 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MEPPDAPAQA11RGAPRLLLLA21VLLAAHPDAQ31AEVRLSVPPL41VEVMRGKSVI
51-10051LDCTPTGTHD61HYMLEWFLTD71RSGARPRLAS81AEMQGSELQV91TMHDTRGRSP
101-150101PYQLDSQGRL111VLAEAQVGDE121RDYVCVVRAG131AAGTAEATAR141LNVFAKPEAT
151-200151EVSPNKGTLS161VMEDSAQEIA171TCNSRNGNPA181PKITWYRNGQ191RLEVPVEMNP
201-250201EGYMTSRTVR211EASGLLSLTS221TLYLRLRKDD231RDASFHCAAH241YSLPEGRHGR
251-300251LDSPTFHLTL261HYPTEHVQFW271VGSPSTPAGW281VREGDTVQLL291CRGDGSPSPE
301-350301YTLFRLQDEQ311EEVLNVNLEG321NLTLEGVTRG331QSGTYGCRVE341DYDAADDVQL
351-400351SKTLELRVAY361LDPLELSEGK371VLSLPLNSSA381VVNCSVHGLP391TPALRWTKDS
401-450401TPLGDGPMLS411LSSITFDSNG421TYVCEASLPT431VPVLSRTQNF441TLLVQGSPEL
451-500451KTAEIEPKAD461GSWREGDEVT471LICSARGHPD481PKLSWSQLGG491SPAEPIPGRQ
501-550501GWVSSSLTLK511VTSALSRDGI521SCEASNPHGN531KRHVFHFGTV541SPQTSQAGVA
551-600551VMAVAVSVGL561LLLVVAVFYC571VRRKGGPCCR581QRREKGAPPP591GEPGLSHSGS
601-628601EQPEQTGLLM611GGASGGARGG621SGGFGDEC
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 53 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.54
|
|
| 125 | - | - | - |
Deep-Palm: 0.96
|
|
| 172 | - | - | - |
GPS-Palm: 0.70
Deep-Palm: 0.40
|
|
| 237 | - | - | - |
Deep-Palm: 0.93
|
|
| 291 | - | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.89
|
|
| 337 | - | - | - |
Deep-Palm: 0.69
|
|
| 384 | - | - | - |
Deep-Palm: 0.95
|
|
| 424 | - | - | - |
Deep-Palm: 0.65
|
|
| 473 | - | - |
cerebral cortex
(36430497)
|
Deep-Palm: 0.86
|
|
| 522 | - | - | - |
Deep-Palm: 0.77
|
|
| 570 | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.98
|
|
| 578 | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.95
|
|
| 579 | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.95
|
|
| 628 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.05
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.364
4
LNCaP
Specificity: 0.267
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.267
4/4 (100.0%)
1
HAP1 cell
Specificity: 0.067
1/1 (100.0%)
1
heart
Specificity: 0.067
1/1 (100.0%)
1
HUVECs
Specificity: 0.067
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Cerebral Cortex (Mass)
Specificity: 0.267
4/4 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 77 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 98 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 357 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 357 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 532 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 570 | C → C | 0.002545 | SNP | Silent | GBM |
| 580 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 628 | C → C | 0.001887 | SNP | Splice Region | UCEC |