Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P51149 | RAB7A; RAB7 | Ras-related protein Rab-7a (EC 3.6.5.2) | Homo sapiens (Human) | 207 aa |
Protein Details: P51149 (RAB7A)
Protein Information
| Accession | P51149 |
|---|---|
| Protein Names | Ras-related protein Rab-7a (EC 3.6.5.2) |
| Gene Symbol | RAB7A; RAB7 |
| Organism | Homo sapiens (Human) |
| Length | 207 aa |
| Isoforms | No isoforms |
| Related PMIDs | 21076176 26876311 29733200 31251020 31382980 32944167 36430497 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.446
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
25
LNCaP cells
Specificity: 0.446
25/46 (54.3%)
10
HAP1 cells
Specificity: 0.179
10/10 (100.0%)
10
293T cells
Specificity: 0.179
10/10 (100.0%)
4
PC3 cells
Specificity: 0.071
4/4 (100.0%)
3
Cerebral cortex
Specificity: 0.054
3/4 (75.0%)
2
Jurkat T cells
Specificity: 0.036
2/25 (8.0%)
1
U937 cells
Specificity: 0.018
1/1 (100.0%)
1
Prefrontal cortex
Specificity: 0.018
1/1 (100.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MTSRKKVLLK11VIILGDSGVG21KTSLMNQYVN31KKFSNQYKAT41IGADFLTKEV
51-10051MVDDRLVTMQ61IWDTAGQERF71QSLGVAFYRG81ADCCVLVFDV91TAPNTFKTLD
101-150101SWRDEFLIQA111SPRDPENFPF121VVLGNKIDLE131NRQVATKRAQ141AWCYSKNNIP
151-200151YFETSAKEAI161NVEQAFQTIA171RNALKQETEV181ELYNEFPEPI191KLDKNDRAKA
201-207201SAESCSC
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 83 | Prediction (Medium) | - | - |
| 84 | Prediction (Low) | - | - |
| 143 | Prediction (Low) | - | - |
| 205 | SWISSPALM Prediction (High) | - | - |
| 207 | SWISSPALM Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 84 | C → C | 0.007299 | SNP | Silent | READ |
| 96 | F → C | 0.002506 | SNP | Missense Mutation | COAD |