Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P51655 Gpc4 Glypican-4 (K-glypican) [Cleaved into: Secreted … Mus musculus (Mouse) 557 aa

Protein Details: P51655 (Gpc4)

Protein Information
AccessionP51655
Protein NamesGlypican-4 (K-glypican) [Cleaved into: Secreted glypican-4]
Gene SymbolGpc4
OrganismMus musculus (Mouse)
Length557 aa
IsoformsNo isoforms
Related PMIDs 35477839 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MARLGLLALL11CTLAALSASL21LAAELKSKSC31SEVRRLYVSK41GFNKNDAPLY
51-10051EINGDHLKIC61PQDYTCCSQE71MEEKYSLQSK81DDFKTVVSEQ91CNHLQAIFAS
101-150101RYKKFDEFFK111ELLENAEKSL121NDMFVKTYGH131LYMQNSELFK141DLFVELKRYY
151-200151VAGNVNLEEM161LNDFWARLLE171RMFRLVNSQY181HFTDEYLECV191SKYTEQLKPF
201-250201GDVPRKLKLQ211VTRAFVAART221FAQGLAVARD231VVSKVSVVNP241TAQCTHALLK
251-300251MIYCSHCRGL261VTVKPCYNYC271SNIMRGCLAN281QGDLDFEWNN291FIDAMLMVAE
301-350301RLEGPFNIES311VMDPIDVKIS321DAIMNMQDNS331VQVSQKVFQG341CGPPKPLPAG
351-400351RISRSISESA361FSARFRPYHP371EQRPTTAAGT381SLDRLVTDVK391EKLKQAKKFW
401-450401SSLPSTVCND411ERMAAGNENE421DDCWNGKGKS431RYLFAVTGNG441LANQGNNPEV
451-500451QVDTSKPDIL461ILRQIMALRV471MTSKMKNAYN481GNDVDFFDIS491DESSGEGSGS
501-550501GCEYQQCPSE511FEYNATDHSG521KSANEKADSA531GGAHAEAKPY541LLAALCILFL
551-557551AVQGEWR
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
11 - - -
GPS-Palm: 0.84
Deep-Palm: 0.97
30 Glypican - -
GPS-Palm: 0.88
Deep-Palm: 0.98
60 - -
Brain (35358180)
Deep-Palm: 0.11
66 - -
Brain (35358180)
Deep-Palm: 0.11
67 - -
Brain (35358180)
Deep-Palm: 0.09
91 - - -
Deep-Palm: 0.67
189 - -
Brain (35358180)
Deep-Palm: 0.67
244 - -
Brain (35358180)
Deep-Palm: 0.33
254 - -
Brain (35358180)
GPS-Palm: 0.68
Deep-Palm: 0.09
257 - -
Brain (35358180)
GPS-Palm: 0.83
Deep-Palm: 0.04
266 - - -
GPS-Palm: 0.76
Deep-Palm: 0.05
270 - - -
GPS-Palm: 0.73
Deep-Palm: 0.10
277 - - -
Deep-Palm: 0.04
341 SWISSPALM DBPTM CYSMODDB Glypican
liver (26165157)
Brain (35358180)
GPS-Palm: 0.86
Deep-Palm: 0.89
408 - - -
Deep-Palm: 0.61
423 - - -
Deep-Palm: 0.28
502 - - -
Deep-Palm: 0.08
507 - - -
Deep-Palm: 0.08
546 - - -
GPS-Palm: 0.74
Deep-Palm: 0.76
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Testis
Specificity: 0.100
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
18
Brain tissue (Mass)
Specificity: 0.900
18/56 (32.1%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine