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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P51681 CCR5; CMKBR5 C-C chemokine receptor type 5 … Homo sapiens (Human) 352 aa

Protein Details: P51681 (CCR5)

Protein Information
Accession P51681
Protein Names C-C chemokine receptor type 5 (C-C CKR-5) (CC-CKR-5) (CCR-5) (CCR5) (CHEMR13) (HIV-1 fusion coreceptor) (CD antigen CD195)
Gene Symbol CCR5; CMKBR5
Organism Homo sapiens (Human)
Length 352 aa
Isoforms No isoforms
Related PMIDs 26111759
Database Sources dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
3
T cells
Specificity: 1.000
3/4 (75.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MDYQVSSPIY11DINYYTSEPC21QKINVKQIAA31RLLPPLYSLV41FIFGFVGNML
51-10051VILILINCKR61LKSMTDIYLL71NLAISDLFFL81LTVPFWAHYA91AAQWDFGNTM
101-150101CQLLTGLYFI111GFFSGIFFII121LLTIDRYLAV131VHAVFALKAR141TVTFGVVTSV
151-200151ITWVVAVFAS161LPGIIFTRSQ171KEGLHYTCSS181HFPYSQYQFW191KNFQTLKIVI
201-250201LGLVLPLLVM211VICYSGILKT221LLRCRNEKKR231HRAVRLIFTI241MIVYFLFWAP
251-300251YNIVLLLNTF261QEFFGLNNCS271SSNRLDQAMQ281VTETLGMTHC291CINPIIYAFV
301-350301GEKFRNYLLV311FFQKHIAKRF321CKCCSIFQQE331APERASSVYT341RSTGEQEISV
351-352351GL
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
58 Prediction (Medium) - -
213 Prediction (Medium) - -
224 Prediction (Medium) - -
269 Prediction (Medium) - -
321 DBPTM SWISSPALM Prediction (High) - -
323 DBPTM SWISSPALM Prediction (High) - -
324 DBPTM SWISSPALM Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
173 G → C 0.002294 SNP Missense Mutation OV
323 C → C 0.002288 SNP Silent STAD