Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P51681 | CCR5 | C-C chemokine receptor type 5 … | Homo sapiens (Human) | 352 aa |
Protein Details: P51681 (CCR5)
Protein Information
| Accession | P51681 |
|---|---|
| Protein Names | C-C chemokine receptor type 5 (C-C CKR-5) (CC-CKR-5) (CCR-5) (CCR5) (CHEMR13) (HIV-1 fusion coreceptor) (CD antigen CD195) |
| Gene Symbol | CCR5 |
| Organism | Homo sapiens (Human) |
| Length | 352 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26111759 |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MDYQVSSPIY11DINYYTSEPC21QKINVKQIAA31RLLPPLYSLV41FIFGFVGNML
51-10051VILILINCKR61LKSMTDIYLL71NLAISDLFFL81LTVPFWAHYA91AAQWDFGNTM
101-150101CQLLTGLYFI111GFFSGIFFII121LLTIDRYLAV131VHAVFALKAR141TVTFGVVTSV
151-200151ITWVVAVFAS161LPGIIFTRSQ171KEGLHYTCSS181HFPYSQYQFW191KNFQTLKIVI
201-250201LGLVLPLLVM211VICYSGILKT221LLRCRNEKKR231HRAVRLIFTI241MIVYFLFWAP
251-300251YNIVLLLNTF261QEFFGLNNCS271SSNRLDQAMQ281VTETLGMTHC291CINPIIYAFV
301-350301GEKFRNYLLV311FFQKHIAKRF321CKCCSIFQQE331APERASSVYT341RSTGEQEISV
351-352351GL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 20 | - | - | - |
Deep-Palm: 0.49
|
|
| 58 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.82
|
|
| 101 | - | - | - |
Deep-Palm: 0.05
|
|
| 178 | - | - | - |
Deep-Palm: 0.07
|
|
| 213 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.97
|
|
| 224 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.97
|
|
| 269 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.58
|
|
| 290 | - | - | - |
Deep-Palm: 0.06
|
|
| 291 | - | - | - |
Deep-Palm: 0.04
|
|
| 321 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.55
|
| 323 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.75
|
| 324 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.58
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Primary T cell
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 173 | G → C | 0.002294 | SNP | Missense Mutation | OV |
| 323 | C → C | 0.002288 | SNP | Silent | STAD |