Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P51828 ADCY7; KIAA0037 Adenylate cyclase type 7 (EC … Homo sapiens (Human) 1080 aa

Protein Details: P51828 (ADCY7)

Protein Information
Accession P51828
Protein Names Adenylate cyclase type 7 (EC 4.6.1.1) (ATP pyrophosphate-lyase 7) (Adenylate cyclase type VII) (Adenylyl cyclase 7)
Gene Symbol ADCY7; KIAA0037
Organism Homo sapiens (Human)
Length 1080 aa
Isoforms No isoforms
Related PMIDs 26111759 37611173
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
4
T cells
Specificity: 0.571
4/4 (100.0%)
3
Jurkat T cells
Specificity: 0.429
3/25 (12.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MPAKGRYFLN11EGEEGPDQDA21LYEKYQLTSQ31HGPLLLTLLL41VAATACVALI
51-10051IIAFSQGDPS61RHQAILGMAF71LVLAVFAALS81VLMYVECLLR91RWLRALALLT
101-150101WACLVALGYV111LVFDAWTKAA121CAWEQVPFFL131FIVFVVYTLL141PFSMRGAVAV
151-200151GAVSTASHLL161VLGSLMGGFT171TPSVRVGLQL181LANAVIFLCG191NLTGAFHKHQ
201-250201MQDASRDLFT211YTVKCIQIRR221KLRIEKRQQE231NLLLSVLPAH241ISMGMKLAII
251-300251ERLKEHGDRR261CMPDNNFHSL271YVKRHQNVSI281LYADIVGFTQ291LASDCSPKEL
301-350301VVVLNELFGK311FDQIAKANEC321MRIKILGDCY331YCVSGLPVSL341PTHARNCVKM
351-400351GLDMCQAIKQ361VREATGVDIN371MRVGIHSGNV381LCGVIGLRKW391QYDVWSHDVS
401-450401LANRMEAAGV411PGRVHITEAT421LKHLDKAYEV431EDGHGQQRDP441YLKEMNIRTY
451-500451LVIDPRSQQP461PPPSQHLPRP471KGDAALKMRA481SVRMTRYLES491WGAARPFAHL
501-550501NHRESVSSGE511THVPNGRRPK521SVPQRHRRTP531DRSMSPKGRS541EDDSYDDEML
551-600551SAIEGLSSTR561PCCSKSDDFY571TFGSIFLEKG581FEREYRLAPI591PRARHDFACA
601-650601SLIFVCILLV611HVLLMPRTAA621LGVSFGLVAC631VLGLVLGLCF641ATKFSRCCPA
651-700651RGTLCTISER661VETQPLLRLT671LAVLTIGSLL681TVAIINLPLM691PFQVPELPVG
701-750701NETGLLAASS711KTRALCEPLP721YYTCSCVLGF731IACSVFLRMS741LEPKVVLLTV
751-800751ALVAYLVLFN761LSPCWQWDCC771GQGLGNLTKP781NGTTSGTPSC791SWKDLKTMTN
801-850801FYLVLFYITL811LTLSRQIDYY821CRLDCLWKKK831FKKEHEEFET841MENVNRLLLE
851-900851NVLPAHVAAH861FIGDKLNEDW871YHQSYDCVCV881MFASVPDFKV891FYTECDVNKE
901-950901GLECLRLLNE911IIADFDELLL921KPKFSGVEKI931KTIGSTYMAA941AGLSVASGHE
951-1000951NQELERQHAH961IGVMVEFSIA971LMSKLDGINR981HSFNSFRLRV991GINHGPVIAG
1001-10501001VIGARKPQYD1011IWGNTVNVAS1021RMESTGELGK1031IQVTEETCTI1041LQGLGYSCEC
1051-10801051RGLINVKGKG1061ELRTYFVCTD1071TAKFQGLGLN
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
87 Prediction (High) - -
103 Prediction (Medium) - -
189 Prediction (Medium) - -
215 Prediction (Medium) - -
295 Prediction (Low) - -
320 Prediction (Medium) - -
355 Prediction (Medium) - -
382 Prediction (Medium) - -
562 Prediction (Low) - -
639 Prediction (Medium) - -
647 Prediction (Low) - -
648 Prediction (Medium) - -
655 Experimental Prediction (Low) - 37611173
716 Prediction (Low) - -
733 Prediction (Low) - -
769 Prediction (Low) - -
770 Prediction (Medium) - -
821 Prediction (High) - -
825 Prediction (Medium) - -
895 Prediction (Low) - -
904 Prediction (Low) - -
1038 Prediction (Low) - -
1048 Prediction (Medium) - -
1050 Prediction (Medium) - -
1068 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
67 G → C 0.001764 SNP Missense Mutation LUAD
80 S → C 0.001014 SNP Missense Mutation BRCA
101 W → C 0.001014 SNP Missense Mutation BRCA
103 C → F 0.001764 SNP Missense Mutation LUAD
163 G → C 0.001764 SNP Missense Mutation LUAD
223 R → C 0.002506 SNP Missense Mutation COAD
329 C → C 0.001887 SNP Silent UCEC
448 R → C 0.005435 SNP Missense Mutation ESCA
630 C → C 0.001887 SNP Silent UCEC
648 C → F 0.001969 SNP Missense Mutation HNSC
715 L → Cfs*23 0.001764 DEL Frame Shift Del LUAD
770 C → C 0.001887 SNP Silent UCEC
775 G → C 0.001764 SNP Missense Mutation LUAD
822 R → C 0.002288 SNP Missense Mutation STAD
877 C → Y 0.001887 SNP Missense Mutation UCEC
895 C → C 0.001887 SNP Silent UCEC
904 C → R 0.001969 SNP Missense Mutation HNSC
991 G → C 0.002033 SNP Missense Mutation LUSC
347* C → ? 0.001969 SNP Nonsense Mutation HNSC