Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P51858 | HDGF | Hepatoma-derived growth factor (HDGF) (High … | Homo sapiens (Human) | 240 aa |
Protein Details: P51858 (HDGF)
Protein Information
| Accession | P51858 |
|---|---|
| Protein Names | Hepatoma-derived growth factor (HDGF) (High mobility group protein 1-like 2) (HMG-1L2) |
| Gene Symbol | HDGF |
| Organism | Homo sapiens (Human) |
| Length | 240 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 31382980 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSRSNRQKEY11KCGDLVFAKM21KGYPHWPARI31DEMPEAAVKS41TANKYQVFFF
51-10051GTHETAFLGP61KDLFPYEESK71EKFGKPNKRK81GFSEGLWEIE91NNPTVKASGY
101-150101QSSQKKSCVE111EPEPEPEAAE121GDGDKKGNAE131GSSDEEGKLV141IDEPAKEKNE
151-200151KGALKRRAGD161LLEDSPKRPK171EAENPEGEEK181EAATLEVERP191LPMEVEKNST
201-240201PSEPGSGRGP211PQEEEEEEDE221EEEATKEDAE231APGIRDHESL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 12 | SWISSPALM DBPTM CYSMODDB | Tudor/PWWP/MBT PWWP domain HEPATOMA-DERIVED GROWTH FACTOR-RELATED | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.03
|
| 108 | - | - | - |
Deep-Palm: 0.82
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
1
U937 cell
Specificity: 0.500
1/1 (100.0%)
1
293T cell
Specificity: 0.500
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 59 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 66 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 168 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 233 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |