Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P52189 Kcnj4 Inward rectifier potassium channel 4 … Mus musculus (Mouse) 445 aa

Protein Details: P52189 (Kcnj4)

Protein Information
AccessionP52189
Protein NamesInward rectifier potassium channel 4 (Inward rectifier K(+) channel Kir2.3) (IRK-3) (Potassium channel, inwardly rectifying subfamily J member 4)
Gene SymbolKcnj4
OrganismMus musculus (Mouse)
Length445 aa
IsoformsNo isoforms
Related PMIDs 35358180
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MHGHNRNGQA11HVPRRKRRNR21FVKKNGQCNV31YFANLSNKSQ41RYMADIFTTC
51-10051VDTRWRYMLM61IFSAAFLVSW71LFFGLLFWWI81AFFHGDLEAS91PSVPAVGGPG
101-150101GNGGESPNAP111KPCIMHVNGF121LGAFLFSVET131QTTIGYGFRC141VTEECPLAVI
151-200151AVVVQSIVGC161VIDSFMIGTI171MAKMARPKKR181AQTLLFSHHA191VISVRDGKLC
201-250201LMWRVGNLRK211SHIVEAHVRA221QLIKPYMTQE231GEYLPLDQRD241LNVGYDIGLD
251-300251RIFLVSPIII261VHEIDEDSPL271YGMGKEELES281EDFEIVVILE291GMVEATAMTT
301-350301QARSSYLASE311ILWGHRFEPV321VFEEKSHYKV331DYSRFHKTYE341VAGTPCCSAR
351-400351ELQESKITVL361PAPPPPPSAF371CYENELALMS381QEEEEMEEEA391AAAAAVAAGL
401-445401GLEAGSKEEA411GIIRMLEFGS421HLDLERMQAA431TLPLDNISYR441RESRI
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
28 Potassium channel, inwardly rectifying, Kir, cytoplasmic Potassium channel, inwardly rectifying, transmembrane domain - -
GPS-Palm: 0.66
Deep-Palm: 0.27
50 SWISSPALM DBPTM CYSMODDB Potassium channel, inwardly rectifying, transmembrane domain Inward rectifier potassium channel transmembrane domain Voltage-gated potassium channels Potassium channel, inwardly rectifying, Kir
Forebrain (28680068)
-
GPS-Palm: 0.90
Deep-Palm: 0.29
113 - - -
Deep-Palm: 0.64
140 - - -
Deep-Palm: 0.61
145 - - -
GPS-Palm: 0.68
Deep-Palm: 0.46
160 - - -
GPS-Palm: 0.75
Deep-Palm: 0.47
200 - - -
GPS-Palm: 0.89
Deep-Palm: 0.62
346 - - -
GPS-Palm: 0.80
Deep-Palm: 0.88
347 - - -
GPS-Palm: 0.87
Deep-Palm: 0.88
371 - - -
Deep-Palm: 0.87
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
Brain
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine