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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P52788 SMS Spermine synthase (SPMSY) (EC 2.5.1.22) … Homo sapiens (Human) 366 aa

Protein Details: P52788 (SMS)

Protein Information
AccessionP52788
Protein NamesSpermine synthase (SPMSY) (EC 2.5.1.22) (Spermidine aminopropyltransferase)
Gene SymbolSMS
OrganismHomo sapiens (Human)
Length366 aa
IsoformsNo isoforms
Related PMIDs 29733200
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAAARHSTLD11FMLGAKADGE21TILKGLQSIF31QEQGMAESVH41TWQDHGYLAT
51-10051YTNKNGSFAN61LRIYPHGLVL71LDLQSYDGDA81QGKEEIDSIL91NKVEERMKEL
101-150101SQDSTGRVKR111LPPIVRGGAI121DRYWPTADGR131LVEYDIDEVV141YDEDSPYQNI
151-200151KILHSKQFGN161ILILSGDVNL171AESDLAYTRA181IMGSGKEDYT191GKDVLILGGG
201-250201DGGILCEIVK211LKPKMVTMVE221IDQMVIDGCK231KYMRKTCGDV241LDNLKGDCYQ
251-300251VLIEDCIPVL261KRYAKEGREF271DYVINDLTAV281PISTSPEEDS291TWEFLRLILD
301-350301LSMKVLKQDG311KYFTQGNCVN321LTEALSLYEE331QLGRLYCPVE341FSKEIVCVPS
351-366351YLELWVFYTV361WKKAKP
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
206 - - -
GPS-Palm: 0.90
Deep-Palm: 0.96
229 - - -
Deep-Palm: 0.28
237 - - -
GPS-Palm: 0.80
Deep-Palm: 0.38
248 - - -
Deep-Palm: 0.77
256 - - -
GPS-Palm: 0.75
Deep-Palm: 0.94
318 - - -
Deep-Palm: 0.77
337 SWISSPALM DBPTM CYSMODDB Spermine/spermidine synthase domain - -
Deep-Palm: 0.96
347 - - -
Deep-Palm: 0.52
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
HAP1 cell
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine