Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P52792 Gck Hexokinase-4 (HK4) (EC 2.7.1.1) (Glucokinase) … Mus musculus (Mouse) 465 aa

Protein Details: P52792 (Gck)

Protein Information
AccessionP52792
Protein NamesHexokinase-4 (HK4) (EC 2.7.1.1) (Glucokinase) (Hexokinase type IV) (HK IV) (Hexokinase-D)
Gene SymbolGck
OrganismMus musculus (Mouse)
Length465 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MLDDRARMEA11TKKEKVEQIL21AEFQLQEEDL31KKVMSRMQKE41MDRGLKLETH
51-10051QEASVKMLPT61YVRSTPEGSE71VGDFLSLDLG81GTNFRVMLVK91VGEGEAGQWS
101-150101VKTKHQMYSI111PEDAMTGTAE121MLFDYISECI131SDFLDKHQMK141HKKLPLGFTF
151-200151SFPVRHEDID161KGILLNWTKG171FKASGAEGNN181IVGLLRDAIK191RRGDFEMDVV
201-250201AMVNDTVATM211ISCYYEDRQC221EVGMIVGTGC231NACYMEEMQN241VELVEGDEGR
251-300251MCVNTEWGAF261GNSGELDEFL271LEYDRMVDES281SVNPGQQLYE291KIIGGKYMGE
301-350301LVRLVLLKLV311EENLLFHGEA321SEQLRTRGAF331ETRFVSQVES341DSGDRRQILN
351-400351ILSTLGLRPS361VADCDIVRRA371CESVSTRAAH381MCSAGLAGVI391NRMRESRSED
401-450401VMRITVGVDG411SVYKLHPSFK421ERFHASVRRL431TPNCEITFIE441SEEGSGRGAA
451-465451LVSAVACKKA461CMLGQ
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
129 - - -
Deep-Palm: 0.29
213 - - -
Deep-Palm: 0.04
220 - - -
Deep-Palm: 0.03
230 - - -
Deep-Palm: 0.05
233 - - -
Deep-Palm: 0.05
252 - - -
GPS-Palm: 0.67
Deep-Palm: 0.27
364 SWISSPALM DBPTM CYSMODDB Hexokinase
Liver (28526873)
liver (26165157)
-
GPS-Palm: 0.94
Deep-Palm: 0.97
371 - - -
GPS-Palm: 0.83
Deep-Palm: 0.83
382 SWISSPALM DBPTM CYSMODDB Hexokinase
liver (26165157)
-
GPS-Palm: 0.76
Deep-Palm: 0.90
434 - - -
Deep-Palm: 0.93
457 - - -
GPS-Palm: 0.84
Deep-Palm: 0.23
461 - - -
GPS-Palm: 0.97
Deep-Palm: 0.10
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
5
Liver
Specificity: 1.000
5/5 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine