Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P52895 | AKR1C2 | Aldo-keto reductase family 1 member … | Homo sapiens (Human) | 323 aa |
Protein Details: P52895 (AKR1C2)
Protein Information
| Accession | P52895 |
|---|---|
| Protein Names | Aldo-keto reductase family 1 member C2 (EC 1.1.1.112) (EC 1.1.1.209) (EC 1.1.1.51) (EC 1.1.1.62) (EC 1.3.1.20) (Chlordecone reductase homolog HAKRD) (Dihydrodiol dehydrogenase 2) (DD-2) (DD2) (Dihydrodiol dehydrogenase/bile acid-binding protein) (DD/BABP) (Type III 3-alpha-hydroxysteroid dehydrogenase) (3-alpha-HSD3) (EC 1.1.1.357) |
| Gene Symbol | AKR1C2 |
| Organism | Homo sapiens (Human) |
| Length | 323 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MDSKYQCVKL11NDGHFMPVLG21FGTYAPAEVP31KSKALEAVKL41AIEAGFHHID
51-10051SAHVYNNEEQ61VGLAIRSKIA71DGSVKREDIF81YTSKLWSNSH91RPELVRPALE
101-150101RSLKNLQLDY111VDLYLIHFPV121SVKPGEEVIP131KDENGKILFD141TVDLCATWEA
151-200151MEKCKDAGLA161KSIGVSNFNH171RLLEMILNKP181GLKYKPVCNQ191VECHPYFNQR
201-250201KLLDFCKSKD211IVLVAYSALG221SHREEPWVDP231NSPVLLEDPV241LCALAKKHKR
251-300251TPALIALRYQ261LQRGVVVLAK271SYNEQRIRQN281VQVFEFQLTS291EEMKAIDGLN
301-323301RNVRYLTLDI311FAGPPNYPFS321DEY
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 7 | - | - | - |
GPS-Palm: 0.77
Deep-Palm: 0.02
|
|
| 145 | - | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.96
|
|
| 154 | - | - | - |
Deep-Palm: 0.80
|
|
| 188 | - | - | - |
Deep-Palm: 0.46
|
|
| 193 | - | - | - |
Deep-Palm: 0.35
|
|
| 206 | SWISSPALM DBPTM CYSMODDB | Aldo/keto reductase family | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.89
|
| 242 | - | - | - |
GPS-Palm: 0.89
Deep-Palm: 0.98
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 263 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |