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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P52907 CAPZA1 F-actin-capping protein subunit alpha-1 (CapZ … Homo sapiens (Human) 286 aa

Protein Details: P52907 (CAPZA1)

Protein Information
Accession P52907
Protein Names F-actin-capping protein subunit alpha-1 (CapZ alpha-1)
Gene Symbol CAPZA1
Organism Homo sapiens (Human)
Length 286 aa
Isoforms No isoforms
Related PMIDs 21076176 29575903 29733200 31251020 32944167 33636221
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.625
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
25
LNCaP cells
Specificity: 0.625
25/46 (54.3%)
4
PC3 cells
Specificity: 0.100
4/4 (100.0%)
4
HAP1 cells
Specificity: 0.100
4/10 (40.0%)
4
293T cells
Specificity: 0.100
4/10 (40.0%)
2
Jurkat T cells
Specificity: 0.050
2/25 (8.0%)
1
Liver membrane
Specificity: 0.025
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MADFDDRVSD11EEKVRIAAKF21ITHAPPGEFN31EVFNDVRLLL41NNDNLLREGA
51-10051AHAFAQYNMD61QFTPVKIEGY71EDQVLITEHG81DLGNSRFLDP91RNKISFKFDH
101-150101LRKEASDPQP111EEADGGLKSW121RESCDSALRA131YVKDHYSNGF141CTVYAKTIDG
151-200151QQTIIACIES161HQFQPKNFWN171GRWRSEWKFT181ITPPTAQVVG191VLKIQVHYYE
201-250201DGNVQLVSHK211DVQDSLTVSN221EAQTAKEFIK231IIENAENEYQ241TAISENYQTM
251-286251SDTTFKALRR261QLPVTRTKID271WNKILSYKIG281KEMQNA
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
124 Prediction (Medium) - -
157 Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) F-actin capping protein alpha subunit 29575903
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
29 F → C 0.003460 SNP Missense Mutation CESC
87 F → C 0.007299 SNP Missense Mutation READ
172 R → C 0.002747 SNP Missense Mutation LIHC
? ? → ? 0.005618 SNP Missense Mutation PAAD