Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P53395 | Dbt | Lipoamide acyltransferase component of branched-chain … | Mus musculus (Mouse) | 482 aa |
Protein Details: P53395 (Dbt)
Protein Information
| Accession | P53395 |
|---|---|
| Protein Names | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (EC 2.3.1.168) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase) |
| Gene Symbol | Dbt |
| Organism | Mus musculus (Mouse) |
| Length | 482 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAAARVLRTW11SQNAVRLTCV21RYFQTFNSAR31VLKPKCVCSV41GYPLFKYSQP
51-10051RHSLRTAAVL61QGQVVQFKLS71DIGEGIREVT81IKEWYVKEGD91TVSQFDSICE
101-150101VQSDKASVTI111TSRYDGVIKR121LYYNLDDIAY131VGKPLIDIET141EALKDSEEDV
151-200151VETPAVSHDE161HTHQEIKGQK171TLATPAVRRL181AMENNIKLSE191VVGSGKDGRI
201-250201LKEDILSFLE211KQTGAILPPS221PKSEITPPPP231QPKDRTFPTP241IAKPPVFTGK
251-300251DRTEPVTGFQ261KAMVKTMSAA271LKIPHFGYCD281EIDLTQLVKL291REELKPVALA
301-350301RGIKLSFMPF311FLKAASLGLL321QFPILNASVD331ENCQNITYKA341SHNIGIAMDT
351-400351ELGLIVPNVK361NVQVRSVFEI371AMELNRLQKL381GSSGQLGTTD391LTGGTFTLSN
401-450401IGSIGGTYAK411PVILPPEVAI421GALGAIKALP431RFDQKGDVYK441AQIMNVSWSA
451-482451DHRVIDGATM461SRFSNLWKSY471LENPAFMLLD481LK
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 19 | - | - | - |
Deep-Palm: 0.81
|
|
| 36 | - | - | - |
Deep-Palm: 0.44
|
|
| 38 | - | - | - |
Deep-Palm: 0.49
|
|
| 99 | - | - | - |
Deep-Palm: 0.37
|
|
| 279 | SWISSPALM DBPTM CYSMODDB | 2-oxoacid dehydrogenases acyltransferase (catalytic domain) |
Liver
(28526873)
liver
(26165157)
| - |
Deep-Palm: 0.95
|
| 333 | SWISSPALM DBPTM CYSMODDB | 2-oxoacid dehydrogenases acyltransferase (catalytic domain) |
Liver
(28526873)
|
Brain
(35358180)
|
Deep-Palm: 0.63
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
6
Liver
Specificity: 0.545
6/6 (100.0%)
2
Testis
Specificity: 0.182
2/2 (100.0%)
1
Brain
Specificity: 0.091
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Liver tissue (Mass)
Specificity: 0.182
2/8 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.