Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P53701 | HCCS | Holocytochrome c-type synthase (EC 4.4.1.17) … | Homo sapiens (Human) | 268 aa |
Protein Details: P53701 (HCCS)
Protein Information
| Accession | P53701 |
|---|---|
| Protein Names | Holocytochrome c-type synthase (EC 4.4.1.17) (Cytochrome c-type heme lyase) |
| Gene Symbol | HCCS |
| Organism | Homo sapiens (Human) |
| Length | 268 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 31251020 32944167 33636221 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGLSPSAPAV11AVQASNASAS21PPSGCPMHEG31KMKGCPVNTE41PSGPTCEKKT
51-10051YSVPAHQERA61YEYVECPIRG71TAAENKENLD81PSNLMPPPNQ91TPAPDQPFAL
101-150101STVREESSIP111RADSEKKWVY121PSEQMFWNAM131LKKGWKWKDE141DISQKDMYNI
151-200151IRIHNQNNEQ161AWKEILKWEA171LHAAECPCGP181SLIRFGGKAK191EYSPRARIRS
201-250201WMGYELPFDR211HDWIINRCGT221EVRYVIDYYD231GGEVNKDYQF241TILDVRPALD
251-268251SLSAVWDRMK261VAWWRWTS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 25 | - | - | - |
Deep-Palm: 0.59
|
|
| 35 | SWISSPALM DBPTM CYSMODDB | - | - | - |
Deep-Palm: 0.13
|
| 46 | SWISSPALM DBPTM CYSMODDB | - | - | - |
Deep-Palm: 0.46
|
| 66 | - | - |
cerebral cortex
(36430497)
|
Deep-Palm: 0.60
|
|
| 176 | - | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.87
|
|
| 178 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.93
|
|
| 218 | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.21
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.300
3
LNCaP
Specificity: 0.300
3/3 (100.0%)
2
HAP1 cell
Specificity: 0.200
2/2 (100.0%)
2
PC3
Specificity: 0.200
2/2 (100.0%)
2
293T cell
Specificity: 0.200
2/2 (100.0%)
1
heart
Specificity: 0.100
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.