Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P53798 Fdft1 Squalene synthase (SQS) (SS) (EC … Mus musculus (Mouse) 416 aa

Protein Details: P53798 (Fdft1)

Protein Information
AccessionP53798
Protein NamesSqualene synthase (SQS) (SS) (EC 2.5.1.21) (FPP:FPP farnesyltransferase) (Farnesyl-diphosphate farnesyltransferase)
Gene SymbolFdft1
OrganismMus musculus (Mouse)
Length416 aa
IsoformsNo isoforms
Related PMIDs 28526873
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MEFVKCLGHP11EEFYNLLRFR21MGGRRNFIPK31MDQDSLSSSL41KTCYKYLNQT
51-10051SRSFAAVIQA61LDGDIRHAIC71VFYLVLRALD81TVEDDMSISV91EKKIPLLCNF
101-150101HTFLYDPEWR111FTESKEKDRQ121VLEDFPTISL131EFRNLAEKYQ141TVIDDICHRM
151-200151GCGMAEFVDK161DVTSKQDWDK171YCHYVAGLVG181IGLSRLFSAS191EFEDPIVGED
201-250201IECANSMGLF211LQKTNIIRDY221LEDQQEGRKF231WPQEVWGRYI241KKLEDFAKPE
251-300251NVDVAVQCLN261ELITNTLQHI271PDVLTYLSRL281RNQSVFNFCA291IPQVMAIATL
301-350301AACYNNQQVF311KGVVKIRKGQ321AVTLMMDATN331MPAVKAIIYQ341YIEEIYHRIP
351-400351NSDPSSSKTK361QVISKIRTQN371LPNCQLISRS381HYSPIYLSFI391MLLAALSWQY
401-416401LSTLSQVTED411YVQREH
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
6 - - -
GPS-Palm: 0.83
Deep-Palm: 0.02
43 Isoprenoid synthase domain superfamily - -
GPS-Palm: 0.80
Deep-Palm: 0.84
70 - - -
GPS-Palm: 0.82
Deep-Palm: 0.81
98 - - -
Deep-Palm: 0.28
147 - - -
Deep-Palm: 0.13
152 - - -
Deep-Palm: 0.09
172 - - -
Deep-Palm: 0.64
203 - - -
Deep-Palm: 0.57
258 - - -
Deep-Palm: 0.67
289 - - -
GPS-Palm: 0.73
Deep-Palm: 0.58
303 - - -
GPS-Palm: 0.81
Deep-Palm: 0.55
374 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
-
GPS-Palm: 0.88
Deep-Palm: 0.69
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
Liver
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine