Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P54687 | BCAT1 | Branched-chain-amino-acid aminotransferase, cytosolic (BCAT(c)) (EC … | Homo sapiens (Human) | 386 aa |
Protein Details: P54687 (BCAT1)
Protein Information
| Accession | P54687 |
|---|---|
| Protein Names | Branched-chain-amino-acid aminotransferase, cytosolic (BCAT(c)) (EC 2.6.1.42) |
| Gene Symbol | BCAT1 |
| Organism | Homo sapiens (Human) |
| Length | 386 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MKDCSNGCSA11ECTGEGGSKE21VVGTFKAKDL31IVTPATILKE41KPDPNNLVFG
51-10051TVFTDHMLTV61EWSSEFGWEK71PHIKPLQNLS81LHPGSSALHY91AVELFEGLKA
101-150101FRGVDNKIRL111FQPNLNMDRM121YRSAVRATLP131VFDKEELLEC141IQQLVKLDQE
151-200151WVPYSTSASL161YIRPTFIGTE171PSLGVKKPTK181ALLFVLLSPV191GPYFSSGTFN
201-250201PVSLWANPKY211VRAWKGGTGD221CKMGGNYGSS231LFAQCEAVDN241GCQQVLWLYG
251-300251EDHQITEVGT261MNLFLYWINE271DGEEELATPP281LDGIILPGVT291RRCILDLAHQ
301-350301WGEFKVSERY311LTMDDLTTAL321EGNRVREMFG331SGTACVVCPV341SDILYKGETI
351-386351HIPTMENGPK361LASRILSKLT371DIQYGREESD381WTIVLS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 4 | - | - | - |
GPS-Palm: 0.85
Deep-Palm: 0.01
|
|
| 8 | - | - | - |
Deep-Palm: 0.02
|
|
| 12 | - | - | - |
Deep-Palm: 0.05
|
|
| 140 | - | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.94
|
|
| 221 | - | - | - |
GPS-Palm: 0.66
Deep-Palm: 0.71
|
|
| 235 | - | - | - |
Deep-Palm: 0.15
|
|
| 242 | - | - | - |
Deep-Palm: 0.17
|
|
| 293 | - | - |
Unknown
(32651440)
|
GPS-Palm: 0.76
Deep-Palm: 0.97
|
|
| 335 | - |
HeLa
(37611173)
| - |
GPS-Palm: 0.68
Deep-Palm: 0.97
|
|
| 338 | - |
HeLa
(37611173)
| - |
GPS-Palm: 0.76
Deep-Palm: 0.93
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
HAP1 cell
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 163 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 163 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 163 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 205 | W → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 335 | C → R | 0.002033 | SNP | Missense Mutation | LUSC |
| 364 | R → C | 0.002506 | SNP | Missense Mutation | COAD |