Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P54869 | Hmgcs2 | Hydroxymethylglutaryl-CoA synthase, mitochondrial (HMG-CoA synthase) … | Mus musculus (Mouse) | 508 aa |
Protein Details: P54869 (Hmgcs2)
Protein Information
| Accession | P54869 |
|---|---|
| Protein Names | Hydroxymethylglutaryl-CoA synthase, mitochondrial (HMG-CoA synthase) (EC 2.3.3.10) (3-hydroxy-3-methylglutaryl coenzyme A synthase) |
| Gene Symbol | Hmgcs2 |
| Organism | Mus musculus (Mouse) |
| Length | 508 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29660268 34884899 35477839 37925639 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.679
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
19
Liver tissue
Specificity: 0.679
19/19 (100.0%)
6
Liver membrane
Specificity: 0.214
6/6 (100.0%)
2
Testis
Specificity: 0.071
2/2 (100.0%)
1
Brain tissue
Specificity: 0.036
1/12 (8.3%)
0
Macrophage Raw 264.7
Specificity: 0.000
0/2 (0.0%)
0
Neural Stem Cells
Specificity: 0.000
0/3 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MQRLLAPARR11VLQVKRAMQE21TSLTPAHLLS31AAQQRFSTIP41PAPLAKTDTW
51-10051PKDVGILALE61VYFPAQYVDQ71TDLEKFNNVE81AGKYTVGLGQ91TRMGFCSVQE
101-150101DINSLCLTVV111QRLMERTKLP121WDAVGRLEVG131TETIIDKSKA141VKTVLMELFQ
151-200151DSGNTDIEGI161DTTNACYGGT171ASLFNAANWM181ESSYWDGRYA191LVVCGDIAVY
201-250201PSGNARPTGG211AGAVAMLIGP221KAPLVLEQGL231RGTHMENAYD241FYKPNLASEY
251-300251PLVDGKLSIQ261CYLRALDRCY271AAYRKKIQNQ281WKQAGNNQPF291TLDDVQYMIF
301-350301HTPFCKMVQK311SLARLMFNDF321LSSSSDKQNN331LYKGLEAFRG341LKLEETYTNK
351-400351DVDKALLKAS361LDMFNQKTKA371SLYLSTNNGN381MYTSSLYGCL391ASLLSHHSAQ
401-450401ELAGSRIGAF411SYGSGLAASF421FSFRVSKDAS431PGSPLEKLVS441SVSDLPKRLD
451-500451SRRRMSPEEF461TEIMNQREQF471YHKVNFSPPG481DTSNLFPGTW491YLERVDEMHR
501-508501RKYARCPV
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 96 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) | Hydroxymethylglutaryl-coenzyme A synthase N terminal | 28526873 |
| 106 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) | Hydroxymethylglutaryl-coenzyme A synthase N terminal | 28526873 |
| 261 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Low) | Hydroxymethylglutaryl-coenzyme A synthase C terminal | 28526873 |
| 269 | Prediction (Medium) | - | - |
| 305 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Low) | Hydroxymethylglutaryl-coenzyme A synthase C terminal | 28526873 |
| 389 | Experimental CYSMODDB SWISSPALM DBPTM | Hydroxymethylglutaryl-coenzyme A synthase C terminal | 28526873 |
| 506 | Prediction (High) | - | - |