Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P55036 | PSMD4 | 26S proteasome non-ATPase regulatory subunit … | Homo sapiens (Human) | 377 aa |
Protein Details: P55036 (PSMD4)
Protein Information
| Accession | P55036 |
|---|---|
| Protein Names | 26S proteasome non-ATPase regulatory subunit 4 (26S proteasome regulatory subunit RPN10) (26S proteasome regulatory subunit S5A) (Antisecretory factor 1) (AF) (ASF) (Multiubiquitin chain-binding protein) |
| Gene Symbol | PSMD4 |
| Organism | Homo sapiens (Human) |
| Length | 377 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MVLESTMVCV11DNSEYMRNGD21FLPTRLQAQQ31DAVNIVCHSK41TRSNPENNVG
51-10051LITLANDCEV61LTTLTPDTGR71ILSKLHTVQP81KGKITFCTGI91RVAHLALKHR
101-150101QGKNHKMRII111AFVGSPVEDN121EKDLVKLAKR131LKKEKVNVDI141INFGEEEVNT
151-200151EKLTAFVNTL161NGKDGTGSHL171VTVPPGPSLA181DALISSPILA191GEGGAMLGLG
201-250201ASDFEFGVDP211SADPELALAL221RVSMEEQRQR231QEEEARRAAA241ASAAEAGIAT
251-300251TGTEDSDDAL261LKMTISQQEF271GRTGLPDLSS281MTEEEQIAYA291MQMSLQGAEF
301-350301GQAESADIDA311SSAMDTSEPA321KEEDDYDVMQ331DPEFLQSVLE341NLPGVDPNNE
351-377351AIRNAMGSLA361SQATKDGKKD371KKEEDKK
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 9 | 26S proteasome non-ATPase regulatory subunit 4 von Willebrand factor A-like domain superfamily von Willebrand factor, type A | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.01
|
|
| 37 | 26S proteasome non-ATPase regulatory subunit 4 von Willebrand factor A-like domain superfamily von Willebrand factor, type A | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.82
|
|
| 58 | - | - | - |
Deep-Palm: 0.91
|
|
| 87 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.87
Deep-Palm: 0.90
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
293T cell
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 87 | C → R | 0.010870 | SNP | Missense Mutation | ACC |
| 91 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 108 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 130 | R → C | 0.001969 | SNP | Missense Mutation | LGG |
| 272 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |