Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P55039 | DRG2 | Developmentally-regulated GTP-binding protein 2 (DRG-2) … | Homo sapiens (Human) | 364 aa |
Protein Details: P55039 (DRG2)
Protein Information
| Accession | P55039 |
|---|---|
| Protein Names | Developmentally-regulated GTP-binding protein 2 (DRG-2) (Translation factor GTPase DRG2) (TRAFAC GTPase DRG2) (EC 3.6.5.-) |
| Gene Symbol | DRG2 |
| Organism | Homo sapiens (Human) |
| Length | 364 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGILEKISEI11EKEIARTQKN21KATEYHLGLL31KAKLAKYRAQ41LLEPSKSASS
51-10051KGEGFDVMKS61GDARVALIGF71PSVGKSTFLS81LMTSTASEAA91SYEFTTLTCI
101-150101PGVIEYKGAN111IQLLDLPGII121EGAAQGKGRG131RQVIAVARTA141DVIIMMLDAT
151-200151KGEVQRSLLE161KELESVGIRL171NKHKPNIYFK181PKKGGGISFN191STVTLTQCSE
201-250201KLVQLILHEY211KIFNAEVLFR221EDCSPDEFID231VIVGNRVYMP241CLYVYNKIDQ
251-300251ISMEEVDRLA261RKPNSVVISC271GMKLNLDYLL281EMLWEYLALT291CIYTKKRGQR
301-350301PDFTDAIILR311KGASVEHVCH321RIHRSLASQF331KYALVWGTST341KYSPQRVGLT
351-364351HTMEHEDVIQ361IVKK
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 99 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.77
|
|
| 198 | - | - | - |
Deep-Palm: 0.66
|
|
| 223 | - | - | - |
Deep-Palm: 0.12
|
|
| 241 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.18
|
|
| 270 | - |
HeLa
(37611173)
| - |
GPS-Palm: 0.89
Deep-Palm: 0.96
|
|
| 291 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.86
|
|
| 319 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.95
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
293T cell
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 72 | S → C | 0.001014 | SNP | Missense Mutation | BRCA |