Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P55085 | F2RL1; GPR11; PAR2 | Proteinase-activated receptor 2 (PAR-2) (Coagulation … | Homo sapiens (Human) | 397 aa |
Protein Details: P55085 (F2RL1)
Protein Information
| Accession | P55085 |
|---|---|
| Protein Names | Proteinase-activated receptor 2 (PAR-2) (Coagulation factor II receptor-like 1) (G-protein coupled receptor 11) (Thrombin receptor-like 1) [Cleaved into: Proteinase-activated receptor 2, alternate cleaved 1; Proteinase-activated receptor 2, alternate cleaved 2] |
| Gene Symbol | F2RL1; GPR11; PAR2 |
| Organism | Homo sapiens (Human) |
| Length | 397 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29575903 31251020 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.556
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
5
LNCaP cells
Specificity: 0.556
5/46 (10.9%)
4
PC3 cells
Specificity: 0.444
4/4 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MRSPSAAWLL11GAAILLAASL21SCSGTIQGTN31RSSKGRSLIG41KVDGTSHVTG
51-10051KGVTVETVFS61VDEFSASVLT71GKLTTVFLPI81VYTIVFVVGL91PSNGMALWVF
101-150101LFRTKKKHPA111VIYMANLALA121DLLSVIWFPL131KIAYHIHGNN141WIYGEALCNV
151-200151LIGFFYGNMY161CSILFMTCLS171VQRYWVIVNP181MGHSRKKANI191AIGISLAIWL
201-250201LILLVTIPLY211VVKQTIFIPA221LNITTCHDVL231PEQLLVGDMF241NYFLSLAIGV
251-300251FLFPAFLTAS261AYVLMIRMLR271SSAMDENSEK281KRKRAIKLIV291TVLAMYLICF
301-350301TPSNLLLVVH311YFLIKSQGQS321HVYALYIVAL331CLSTLNSCID341PFVYYFVSHD
351-397351FRDHAKNALL361CRSVRTVKQM371QVSLTSKKHS381RKSSSYSSSS391TTVKTSY
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 22 | Prediction (Medium) | - | - |
| 168 | Prediction (Medium) | - | - |
| 299 | Prediction (Medium) | - | - |
| 361 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) | - | 29575903 |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 60 | S → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 226 | C → S | 0.002033 | SNP | Missense Mutation | LUSC |
| 333 | S → C | 0.003460 | SNP | Missense Mutation | CESC |
| 361 | C → C | 0.002506 | SNP | Silent | COAD |