Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P55085 | F2RL1 | Proteinase-activated receptor 2 (PAR-2) (Coagulation … | Homo sapiens (Human) | 397 aa |
Protein Details: P55085 (F2RL1)
Protein Information
| Accession | P55085 |
|---|---|
| Protein Names | Proteinase-activated receptor 2 (PAR-2) (Coagulation factor II receptor-like 1) (G-protein coupled receptor 11) (Thrombin receptor-like 1) [Cleaved into: Proteinase-activated receptor 2, alternate cleaved 1; Proteinase-activated receptor 2, alternate cleaved 2] |
| Gene Symbol | F2RL1 |
| Organism | Homo sapiens (Human) |
| Length | 397 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MRSPSAAWLL11GAAILLAASL21SCSGTIQGTN31RSSKGRSLIG41KVDGTSHVTG
51-10051KGVTVETVFS61VDEFSASVLT71GKLTTVFLPI81VYTIVFVVGL91PSNGMALWVF
101-150101LFRTKKKHPA111VIYMANLALA121DLLSVIWFPL131KIAYHIHGNN141WIYGEALCNV
151-200151LIGFFYGNMY161CSILFMTCLS171VQRYWVIVNP181MGHSRKKANI191AIGISLAIWL
201-250201LILLVTIPLY211VVKQTIFIPA221LNITTCHDVL231PEQLLVGDMF241NYFLSLAIGV
251-300251FLFPAFLTAS261AYVLMIRMLR271SSAMDENSEK281KRKRAIKLIV291TVLAMYLICF
301-350301TPSNLLLVVH311YFLIKSQGQS321HVYALYIVAL331CLSTLNSCID341PFVYYFVSHD
351-397351FRDHAKNALL361CRSVRTVKQM371QVSLTSKKHS381RKSSSYSSSS391TTVKTSY
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 22 | Prokaryotic membrane lipoprotein lipid attachment site profile. Protease-activated receptor 2 | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.97
|
|
| 148 | - | - | - |
Deep-Palm: 0.01
|
|
| 161 | - | - | - |
Deep-Palm: 0.03
|
|
| 168 | - | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.03
|
|
| 226 | - | - | - |
Deep-Palm: 0.56
|
|
| 299 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.41
|
|
| 331 | - | - | - |
Deep-Palm: 0.07
|
|
| 338 | - | - | - |
Deep-Palm: 0.05
|
|
| 361 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.89
Deep-Palm: 0.88
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 60 | S → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 226 | C → S | 0.002033 | SNP | Missense Mutation | LUSC |
| 333 | S → C | 0.003460 | SNP | Missense Mutation | CESC |
| 361 | C → C | 0.002506 | SNP | Silent | COAD |