Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P55212 | CASP6 | Caspase-6 (CASP-6) (CSP-6) (EC 3.4.22.59) … | Homo sapiens (Human) | 293 aa |
Protein Details: P55212 (CASP6)
Protein Information
| Accession | P55212 |
|---|---|
| Protein Names | Caspase-6 (CASP-6) (CSP-6) (EC 3.4.22.59) (Apoptotic protease Mch-2) [Cleaved into: Caspase-6 subunit p18 (Caspase-6 subunit p20); Caspase-6 subunit p11 (Caspase-6 subunit p10)] |
| Gene Symbol | CASP6 |
| Organism | Homo sapiens (Human) |
| Length | 293 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | PTMDdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSSASGLRRG11HPAGGEENMT21ETDAFYKREM31FDPAEKYKMD41HRRRGIALIF
51-10051NHERFFWHLT61LPERRGTCAD71RDNLTRRFSD81LGFEVKCFND91LKAEELLLKI
101-150101HEVSTVSHAD111ADCFVCVFLS121HGEGNHIYAY131DAKIEIQTLT141GLFKGDKCHS
151-200151LVGKPKIFII161QACRGNQHDV171PVIPLDVVDN181QTEKLDTNIT191EVDAASVYTL
201-250201PAGADFLMCY211SVAEGYYSHR221ETVNGSWYIQ231DLCEMLGKYG241SSLEFTELLT
251-293251LVNRKVSQRR261VDFCKDPSAI271GKKQVPCFAS281MLTKKLHFFP291KSN
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 68 | - | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.85
|
|
| 87 | - | - | - |
Deep-Palm: 0.98
|
|
| 113 | - | - | - |
Deep-Palm: 0.05
|
|
| 116 | - | - | - |
Deep-Palm: 0.05
|
|
| 148 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.95
|
|
| 163 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.83
|
|
| 209 | - | - | - |
Deep-Palm: 0.88
|
|
| 233 | - | - | - |
Deep-Palm: 0.72
|
|
| 264 | PTMD DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.93
|
| 277 | PTMD DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.89
Deep-Palm: 0.76
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 128 | Y → Cfs*3 | 0.003460 | DEL | Frame Shift Del | CESC |
| 216 | Y → C | 0.002294 | SNP | Missense Mutation | OV |
| 259 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |