Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P56593 Cyp2a12 Cytochrome P450 2A12 (EC 1.14.14.1) … Mus musculus (Mouse) 492 aa

Protein Details: P56593 (Cyp2a12)

Protein Information
AccessionP56593
Protein NamesCytochrome P450 2A12 (EC 1.14.14.1) (CYPIIA12) (Steroid hormones 7-alpha-hydroxylase) (Testosterone 7-alpha-hydroxylase)
Gene SymbolCyp2a12
OrganismMus musculus (Mouse)
Length492 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MLGSGLLLLA11ILAFLSVMVL21VSVWQQKIRG31KLPPGPIPLP41FIGNYLQLNR
51-10051KDVYSSITQL61QEHYGPVFTI71HLGPRRVVVL81YGYDAVKEAL91VDHAEEFSGR
101-150101GEQATFNTLF111KGYGVAFSNG121ERAKQLRRFS131IATLRDFGMG141KRGVEERIQE
151-200151EAGCLIKMLQ161GTCGAPIDPT171IYLSKTASNV181ISSIVFGDRF191NYEDKEFLSL
201-250201LQMMGQVNKF211AASPTGQLYD221MFHSVMKYLP231GPQQQIIKDS241HKLEDFMIQK
251-300251VKQNQSTLDP261NSPRDFIDSF271LIHMQKEKYV281NSEFHMKNLV291MTSLNLFFAG
301-350301SETVSSTLRY311GFLLLMKHPD321VEAKVHEEID331RVIGRNRQPQ341YEDHMKMPYT
351-400351QAVINEIQRF361SNFAPLGIPR371RITKDTSFRG381FFLPKGTEVF391PILGSLMTDP
401-450401KFFSSPKDFN411PQHFLDDKGQ421LKKIPAFLPF431STGKRFCLGD441SLAKMELFLF
451-492451FTTILQNFRF461KFPRKLEDIN471ESPTPEGFTR481IIPKYTMSFV491PI
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
154 - - -
Deep-Palm: 0.94
163 SWISSPALM DBPTM CYSMODDB Cytochrome P450
Liver (28526873)
-
Deep-Palm: 0.84
437 SWISSPALM DBPTM CYSMODDB Cytochrome P450
Liver (28526873)
-
GPS-Palm: 0.95
Deep-Palm: 0.97
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
6
Liver
Specificity: 1.000
6/6 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine