Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P57780 | Actn4 | Alpha-actinin-4 (Non-muscle alpha-actinin 4) | Mus musculus (Mouse) | 912 aa |
Protein Details: P57780 (Actn4)
Protein Information
| Accession | P57780 |
|---|---|
| Protein Names | Alpha-actinin-4 (Non-muscle alpha-actinin 4) |
| Gene Symbol | Actn4 |
| Organism | Mus musculus (Mouse) |
| Length | 912 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 34200797 34884899 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MVDYHAANQA11YQYGPNSGGG21NGAGGGGSMG31DYMAQEDDWD41RDLLLDPAWE
51-10051KQQRKTFTAW61CNSHLRKAGT71QIENIDEDFR81DGLKLMLLLE91VISGERLPKP
101-150101ERGKMRVHKI111NNVNKALDFI121ASKGVKLVSI131GAEEIVDGNA141KMTLGMIWTI
151-200151ILRFAIQDIS161VEETSAKEGL171LLWCQRKTAP181YKNVNVQNFH191ISWKDGLAFN
201-250201ALIHRHRPEL211IEYDKLRKDD221PVTNLNNAFE231VAEKYLDIPK241MLDAEDIVNT
251-300251ARPDEKAIMT261YVSSFYHAFS271GAQKAETAAN281RICKVLAVNQ291ENEHLMEDYE
301-350301RLASDLLEWI311RRTIPWLEDR321VPQKTIQEMQ331QKLEDFRDYR341RVHKPPKVQE
351-400351KCQLEINFNT361LQTKLRLSNR371PAFMPSEGRM381VSDINNGWQH391LEQAEKGYEE
401-450401WLLNEIRRLE411RLDHLAEKFR421QKASIHEAWT431DGKEAMLKQR441DYETATLSDI
451-500451KALIRKHEAF461ESDLAAHQDR471VEQIAAIAQE481LNELDYYDSH491NVNTRCQKIC
501-550501DQWDNLGSLT511HSRREALEKT521EKQLETIDQL531HLEYAKRAAP541FNNWMESAME
551-600551DLQDMFIVHT561IEEIEGLISA571HDQFKSTLPD581ADREREAILA591IHKEAQRIAE
601-650601SNHIKLSGSN611PYTTVTPQII621NSKWEKVQQL631VPKRDHALLE641EQSKQQSNEH
651-700651LRRQFASQAN661MVGPWIQTKM671EEIGRISIEM681NGTLEDQLSH691LKQYERSIVD
701-750701YKPSLDLLEQ711QHQLIQEALI721FDNKHTNYTM731EHIRVGWEQL741LTTIARTINE
751-800751VENQILTRDA761KGISQEQMQE771FRASFNHFDK781DHGGALGPEE791FKACLISLGY
801-850801DVENDRQGDA811EFNRIMSVVD821PNHSGLVTFQ831AFIDFMSRET841TDTDTADQVI
851-900851ASFKVLAGDK861NFITAEELRR871ELPPDQAEYC881IARMAPYQGP891DAAPGALDYK
901-912901SFSTALYGES911DL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 61 | - | - |
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.87
Deep-Palm: 0.68
|
|
| 174 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.96
Deep-Palm: 0.96
|
|
| 283 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.81
|
|
| 352 | - | - | - |
Deep-Palm: 0.82
|
|
| 496 | - | - | - |
Deep-Palm: 0.05
|
|
| 500 | - |
brain
(39008777)
|
Brain
(35358180)
|
Deep-Palm: 0.05
|
|
| 794 | - | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.93
|
|
| 880 | Ca2+ insensitive EF hand |
Brain
(34200797)
|
Brain
(31311849)
|
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.556
5
Liver
Specificity: 0.208
5/5 (100.0%)
4
Brain
Specificity: 0.167
4/4 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.867
13
Brain tissue (Mass)
Specificity: 0.542
13/56 (23.2%)
2
Liver tissue (Mass)
Specificity: 0.083
2/8 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.