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UniProt ID Gene Symbol Protein Name Organism Length Action
P58137 Acot8 Acyl-coenzyme A thioesterase 8 (Acyl-CoA … Mus musculus (Mouse) 320 aa

Protein Details: P58137 (Acot8)

Protein Information
AccessionP58137
Protein NamesAcyl-coenzyme A thioesterase 8 (Acyl-CoA thioesterase 8) (EC 3.1.2.1) (EC 3.1.2.11) (EC 3.1.2.2) (EC 3.1.2.3) (EC 3.1.2.5) (Choloyl-coenzyme A thioesterase) (EC 3.1.2.27) (Peroxisomal acyl-CoA thioesterase 2) (PTE-2) (Peroxisomal acyl-coenzyme A thioester hydrolase 1) (PTE-1) (Peroxisomal long-chain acyl-CoA thioesterase 1)
Gene SymbolAcot8
OrganismMus musculus (Mouse)
Length320 aa
IsoformsNo isoforms
Related PMIDs 34884899 37925639
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MSAPEGLGDA11HGDADRGDLS21GDLRSVLVTS31VLNLEPLDED41LYRGRHYWVP
51-10051TSQRLFGGQI61MGQALVAAAK71SVSEDVHVHS81LHCYFVRAGD91PKVPVLYHVE
101-150101RIRTGASFSV111RAVKAVQHGK121AIFICQASFQ131QMQPSPLQHQ141FSMPSVPPPE
151-200151DLLDHEALID161QYLRDPNLHK171KYRVGLNRVA181AQEVPIEIKV191VNPPTLTQLQ
201-250201ALEPKQMFWV211RARGYIGEGD221IKMHCCVAAY231ISDYAFLGTA241LLPHQSKYKV
251-300251NFMASLDHSM261WFHAPFRADH271WMLYECESPW281AGGSRGLVHG291RLWRRDGVLA
301-320301VTCAQEGVIR311LKPQVSESKL
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
83 - - -
Deep-Palm: 0.78
125 - - -
GPS-Palm: 0.75
Deep-Palm: 0.60
225 - - -
Deep-Palm: 0.28
226 - - -
Deep-Palm: 0.25
276 - - -
GPS-Palm: 0.66
Deep-Palm: 0.22
303 - - -
GPS-Palm: 0.90
Deep-Palm: 0.98
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
Liver
Specificity: 1.000
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine