Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P60033 | CD81; TAPA1; TSPAN28 | CD81 antigen (26 kDa cell … | Homo sapiens (Human) | 236 aa |
Protein Details: P60033 (CD81)
Protein Information
| Accession | P60033 |
|---|---|
| Protein Names | CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the antiproliferative antibody 1) (Tetraspanin-28) (Tspan-28) (CD antigen CD81) |
| Gene Symbol | CD81; TAPA1; TSPAN28 |
| Organism | Homo sapiens (Human) |
| Length | 236 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 19801377 21076176 24357059 25914232 26876311 29575903 29733200 31251020 33636221 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.607
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
34
LNCaP cells
Specificity: 0.607
34/46 (73.9%)
6
Jurkat T cells
Specificity: 0.107
6/25 (24.0%)
4
HAP1 cells
Specificity: 0.071
4/10 (40.0%)
4
293T cells
Specificity: 0.071
4/10 (40.0%)
3
CEMx174 cells
Specificity: 0.054
3/3 (100.0%)
2
DU145 cells
Specificity: 0.036
2/2 (100.0%)
1
Endothelial cells
Specificity: 0.018
1/2 (50.0%)
1
Prefrontal cortex
Specificity: 0.018
1/1 (100.0%)
1
Liver membrane
Specificity: 0.018
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGVEGCTKCI11KYLLFVFNFV21FWLAGGVILG31VALWLRHDPQ41TTNLLYLELG
51-10051DKPAPNTFYV61GIYILIAVGA71VMMFVGFLGC81YGAIQESQCL91LGTFFTCLVI
101-150101LFACEVAAGI111WGFVNKDQIA121KDVKQFYDQA131LQQAVVDDDA141NNAKAVVKTF
151-200151HETLDCCGSS161TLTALTTSVL171KNNLCPSGSN181IISNLFKEDC191HQKIDDLFSG
201-236201KLYLIGIAAI211VVAVIMIFEM221ILSMVLCCGI231RNSSVY
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 6 | DBPTM SWISSPALM Prediction (High) | - | - |
| 9 | DBPTM SWISSPALM Prediction (Medium) | - | - |
| 80 | DBPTM SWISSPALM Prediction (Low) | Tetraspanin family | - |
| 89 | DBPTM SWISSPALM | Tetraspanin family | - |
| 97 | DBPTM SWISSPALM | Tetraspanin family | - |
| 104 | DBPTM SWISSPALM | Tetraspanin family | - |
| 156 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | - | - |
| 157 | CYSMODDB SWISSPALM DBPTM Prediction (High) | - | - |
| 175 | Experimental Prediction (Low) | - | 29575903 |
| 190 | Prediction (Low) | - | - |
| 227 | DBPTM SWISSPALM Prediction (High) | - | - |
| 228 | DBPTM SWISSPALM Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 157 | C → F | 0.003559 | SNP | Missense Mutation | KIRP |
| ? | ? → ? | 0.001887 | SNP | Missense Mutation | UCEC |