Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P60468 | SEC61B | Protein transport protein Sec61 subunit … | Homo sapiens (Human) | 96 aa |
Protein Details: P60468 (SEC61B)
Protein Information
| Accession | P60468 |
|---|---|
| Protein Names | Protein transport protein Sec61 subunit beta |
| Gene Symbol | SEC61B |
| Organism | Homo sapiens (Human) |
| Length | 96 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 31251020 32944167 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MPGPTPSGTN11VGSSGRSPSK21AVAARAAGST31VRQRKNASCG41TRSAGRTTSA
51-9651GTGGMWRFYT61EDSPGLKVGP71VPVLVMSLLF81IASVFMLHIW91GKYTRS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 39 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.94
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.286
2
LNCaP
Specificity: 0.286
2/2 (100.0%)
2
PC3
Specificity: 0.286
2/2 (100.0%)
2
293T cell
Specificity: 0.286
2/2 (100.0%)
1
HAP1 cell
Specificity: 0.143
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 39 | C → R | 0.002288 | SNP | Missense Mutation | STAD |
| 55 | M → Cfs*22 | 0.002288 | DEL | Frame Shift Del | STAD |
| 55 | M → Cfs*22 | 0.002506 | DEL | Frame Shift Del | COAD |
| 55 | M → Cfs*22 | 0.001887 | DEL | Frame Shift Del | UCEC |
| ? | ? → ? | 0.001887 | SNP | Missense Mutation | UCEC |