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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P60468 SEC61B Protein transport protein Sec61 subunit … Homo sapiens (Human) 96 aa

Protein Details: P60468 (SEC61B)

Protein Information
Accession P60468
Protein Names Protein transport protein Sec61 subunit beta
Gene Symbol SEC61B
Organism Homo sapiens (Human)
Length 96 aa
Isoforms No isoforms
Related PMIDs 29733200 31251020 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.550
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
22
LNCaP cells
Specificity: 0.550
22/46 (47.8%)
10
293T cells
Specificity: 0.250
10/10 (100.0%)
6
HAP1 cells
Specificity: 0.150
6/10 (60.0%)
2
PC3 cells
Specificity: 0.050
2/4 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MPGPTPSGTN11VGSSGRSPSK21AVAARAAGST31VRQRKNASCG41TRSAGRTTSA
51-9651GTGGMWRFYT61EDSPGLKVGP71VPVLVMSLLF81IASVFMLHIW91GKYTRS
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
39 CYSMODDB SWISSPALM DBPTM Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
39 C → R 0.002288 SNP Missense Mutation STAD
55 M → Cfs*22 0.002288 DEL Frame Shift Del STAD
55 M → Cfs*22 0.002506 DEL Frame Shift Del COAD
55 M → Cfs*22 0.001887 DEL Frame Shift Del UCEC
? ? → ? 0.001887 SNP Missense Mutation UCEC