Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P60709 | ACTB | Actin, cytoplasmic 1 (EC 3.6.4.-) … | Homo sapiens (Human) | 375 aa |
Protein Details: P60709 (ACTB)
Protein Information
| Accession | P60709 |
|---|---|
| Protein Names | Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed] |
| Gene Symbol | ACTB |
| Organism | Homo sapiens (Human) |
| Length | 375 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 21076176 22496122 25914232 29733200 31382980 33636221 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
10
HAP1 cells
Specificity: 0.400
10/10 (100.0%)
6
Jurkat T cells
Specificity: 0.240
6/25 (24.0%)
4
293T cells
Specificity: 0.160
4/10 (40.0%)
2
CEMx174 cells
Specificity: 0.080
2/3 (66.7%)
1
U937 cells
Specificity: 0.040
1/1 (100.0%)
1
Endothelial cells
Specificity: 0.040
1/2 (50.0%)
1
Liver membrane
Specificity: 0.040
1/1 (100.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MDDDIAALVV11DNGSGMCKAG21FAGDDAPRAV31FPSIVGRPRH41QGVMVGMGQK
51-10051DSYVGDEAQS61KRGILTLKYP71IEHGIVTNWD81DMEKIWHHTF91YNELRVAPEE
101-150101HPVLLTEAPL111NPKANREKMT121QIMFETFNTP131AMYVAIQAVL141SLYASGRTTG
151-200151IVMDSGDGVT161HTVPIYEGYA171LPHAILRLDL181AGRDLTDYLM191KILTERGYSF
201-250201TTTAEREIVR211DIKEKLCYVA221LDFEQEMATA231ASSSSLEKSY241ELPDGQVITI
251-300251GNERFRCPEA261LFQPSFLGME271SCGIHETTFN281SIMKCDVDIR291KDLYANTVLS
301-350301GGTTMYPGIA311DRMQKEITAL321APSTMKIKII331APPERKYSVW341IGGSILASLS
351-375351TFQQMWISKQ361EYDESGPSIV371HRKCF
Palmitoylation Sites Details
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 69 | Y → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 86 | W → C | 0.027027 | SNP | Missense Mutation | DLBC |
| 91 | Y → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 156 | G → C | 0.002545 | SNP | Missense Mutation | GBM |
| 177 | R → C | 0.002020 | SNP | Missense Mutation | PRAD |
| 177 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 196 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 196 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 210 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 217 | C → Y | 0.027027 | SNP | Missense Mutation | DLBC |
| 217 | C → C | 0.001969 | SNP | Silent | LGG |
| 240 | Y → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 265 | S → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 279 | F → C | 0.002545 | SNP | Missense Mutation | GBM |
| 281 | S → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 294 | Y → C | 0.002288 | SNP | Missense Mutation | STAD |
| 335 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 372 | R → C | 0.002506 | SNP | Missense Mutation | COAD |