Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P60710 | Actb | Actin, cytoplasmic 1 (Beta-actin) (EC … | Mus musculus (Mouse) | 375 aa |
Protein Details: P60710 (Actb)
Protein Information
| Accession | P60710 |
|---|---|
| Protein Names | Actin, cytoplasmic 1 (Beta-actin) (EC 3.6.4.-) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed] |
| Gene Symbol | Actb |
| Organism | Mus musculus (Mouse) |
| Length | 375 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29733200 31311849 34200797 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MDDDIAALVV11DNGSGMCKAG21FAGDDAPRAV31FPSIVGRPRH41QGVMVGMGQK
51-10051DSYVGDEAQS61KRGILTLKYP71IEHGIVTNWD81DMEKIWHHTF91YNELRVAPEE
101-150101HPVLLTEAPL111NPKANREKMT121QIMFETFNTP131AMYVAIQAVL141SLYASGRTTG
151-200151IVMDSGDGVT161HTVPIYEGYA171LPHAILRLDL181AGRDLTDYLM191KILTERGYSF
201-250201TTTAEREIVR211DIKEKLCYVA221LDFEQEMATA231ASSSSLEKSY241ELPDGQVITI
251-300251GNERFRCPEA261LFQPSFLGME271SCGIHETTFN281SIMKCDVDIR291KDLYANTVLS
301-350301GGTTMYPGIA311DRMQKEITAL321APSTMKIKII331APPERKYSVW341IGGSILASLS
351-375351TFQQMWISKQ361EYDESGPSIV371HRKCF
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 17 | ATPase, nucleotide binding domain Actin family | - |
NSC
(31772009)
Brain
(35358180)
Macrophage Raw 264.7
(29217618)
|
Deep-Palm: 0.93
|
|
| 217 | SWISSPALM DBPTM CYSMODDB | Actin |
Liver
(28526873)
|
Liver
(34884899)
NSC
(31772009)
Brain
(35358180)
|
GPS-Palm: 0.68
Deep-Palm: 0.94
|
| 257 | Actin |
Liver
(28526873)
|
Brain
(35358180)
|
Deep-Palm: 0.69
|
|
| 272 | SWISSPALM DBPTM CYSMODDB | Actin |
Liver
(28526873)
|
Brain
(35358180)
|
Deep-Palm: 0.14
|
| 285 | Actin |
Brain
(31311849)
|
Brain
(35358180)
|
Deep-Palm: 0.18
|
|
| 374 | - | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.556
5
Brain
Specificity: 0.238
5/5 (100.0%)
4
Liver
Specificity: 0.190
4/4 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
9
Macrophage Raw 264.7 (Mass)
Specificity: 0.429
9/10 (90.0%)
3
Brain tissue (Mass)
Specificity: 0.143
3/56 (5.4%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.