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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P60763 RAC3 Ras-related C3 botulinum toxin substrate … Homo sapiens (Human) 192 aa

Protein Details: P60763 (RAC3)

Protein Information
AccessionP60763
Protein NamesRas-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene SymbolRAC3
OrganismHomo sapiens (Human)
Length192 aa
IsoformsNo isoforms
Related PMIDs 26876311 31251020
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MQAIKCVVVG11DGAVGKTCLL21ISYTTNAFPG31EYIPTVFDNY41SANVMVDGKP
51-10051VNLGLWDTAG61QEDYDRLRPL71SYPQTDVFLI81CFSLVSPASF91ENVRAKWYPE
101-150101VRHHCPHTPI111LLVGTKLDLR121DDKDTIERLR131DKKLAPITYP141QGLAMAREIG
151-192151SVKYLECSAL161TQRGLKTVFD171EAIRAVLCPP181PVKKPGKKCT191VF
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
6 SWISSPALM DBPTM CYSMODDB Ras family P-loop containing nucleoside triphosphate hydrolase Small GTPase
SW480 cell line (26865113)
cerebral cortex (36430497)
GPS-Palm: 0.92
Deep-Palm: 0.09
18 P-loop containing nucleoside triphosphate hydrolase Transforming protein P21 ras signature Small GTPase Small GTPase Rho - -
GPS-Palm: 0.76
Deep-Palm: 0.97
81 - - -
Deep-Palm: 0.95
105 - - -
Deep-Palm: 0.98
157 SWISSPALM DBPTM CYSMODDB - -
cerebral cortex (36430497)
Unknown (32651440)
GPS-Palm: 0.93
Deep-Palm: 0.98
178 - -
cerebral cortex (36430497)
GPS-Palm: 0.87
Deep-Palm: 0.97
189 - - -
GPS-Palm: 0.96
Deep-Palm: 0.02
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
2
LNCaP
Specificity: 0.667
2/2 (100.0%)
1
frontal cortex
Specificity: 0.333
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine