Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P61026 | RAB10 | Ras-related protein Rab-10 (EC 3.6.5.2) | Homo sapiens (Human) | 200 aa |
Protein Details: P61026 (RAB10)
Protein Information
| Accession | P61026 |
|---|---|
| Protein Names | Ras-related protein Rab-10 (EC 3.6.5.2) |
| Gene Symbol | RAB10 |
| Organism | Homo sapiens (Human) |
| Length | 200 aa |
| Isoforms | No isoforms |
| Related PMIDs | 22496122 26876311 29733200 31251020 31382980 32944167 36430497 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAKKTYDLLF11KLLLIGDSGV21GKTCVLFRFS31DDAFNTTFIS41TIGIDFKIKT
51-10051VELQGKKIKL61QIWDTAGQER71FHTITTSYYR81GAMGIMLVYD91ITNGKSFENI
101-150101SKWLRNIDEH111ANEDVERMLL121GNKCDMDDKR131VVPKGKGEQI141AREHGIRFFE
151-200151TSAKANINIE161KAFLTLAEDI171LRKTPVKEPN181SENVDISSGG191GVTGWKSKCC
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 24 | SWISSPALM DBPTM CYSMODDB | Ras family Small GTPase superfamily, Rab P-loop containing nucleoside triphosphate hydrolase Transforming protein P21 ras signature Small GTPase small GTPase Rab1 family profile. | - | - |
Deep-Palm: 0.94
|
| 124 | - | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.95
|
|
| 199 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.02
|
|
| 200 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.01
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.250
4
PC3
Specificity: 0.250
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.250
4/4 (100.0%)
2
LNCaP
Specificity: 0.125
2/2 (100.0%)
2
293T cell
Specificity: 0.125
2/2 (100.0%)
1
HAP1 cell
Specificity: 0.062
1/1 (100.0%)
1
U937 cell
Specificity: 0.062
1/1 (100.0%)
1
EC cell
Specificity: 0.062
1/1 (100.0%)
1
frontal cortex
Specificity: 0.062
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 28 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |