Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P61158 | ACTR3; ARP3 | Actin-related protein 3 (Actin-like protein … | Homo sapiens (Human) | 418 aa |
Protein Details: P61158 (ACTR3)
Protein Information
| Accession | P61158 |
|---|---|
| Protein Names | Actin-related protein 3 (Actin-like protein 3) |
| Gene Symbol | ACTR3; ARP3 |
| Organism | Homo sapiens (Human) |
| Length | 418 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29575903 29733200 31251020 32944167 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.611
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
22
LNCaP cells
Specificity: 0.611
22/46 (47.8%)
4
PC3 cells
Specificity: 0.111
4/4 (100.0%)
4
HAP1 cells
Specificity: 0.111
4/10 (40.0%)
4
293T cells
Specificity: 0.111
4/10 (40.0%)
2
Cerebral cortex
Specificity: 0.056
2/4 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAGRLPACVV11DCGTGYTKLG21YAGNTEPQFI31IPSCIAIKES41AKVGDQAQRR
51-10051VMKGVDDLDF61FIGDEAIEKP71TYATKWPIRH81GIVEDWDLME91RFMEQVIFKY
101-150101LRAEPEDHYF111LLTEPPLNTP121ENREYTAEIM131FESFNVPGLY141IAVQAVLALA
151-200151ASWTSRQVGE161RTLTGTVIDS171GDGVTHVIPV181AEGYVIGSCI191KHIPIAGRDI
201-250201TYFIQQLLRD211REVGIPPEQS221LETAKAVKER231YSYVCPDLVK241EFNKYDTDGS
251-300251KWIKQYTGIN261AISKKEFSID271VGYERFLGPE281IFFHPEFANP291DFTQPISEVV
301-350301DEVIQNCPID311VRRPLYKNIV321LSGGSTMFRD331FGRRLQRDLK341RTVDARLKLS
351-400351EELSGGRLKP361KPIDVQVITH371HMQRYAVWFG381GSMLASTPEF391YQVCHTKKDY
401-418401EEIGPSICRH411NPVFGVMS
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 8 | CYSMODDB SWISSPALM DBPTM Prediction (High) | Actin | - |
| 12 | CYSMODDB SWISSPALM DBPTM Prediction (Low) | Actin | - |
| 34 | Prediction (Medium) | - | - |
| 189 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) | Actin | 29575903 |
| 235 | Prediction (Medium) | - | - |
| 307 | Prediction (Low) | - | - |
| 394 | Prediction (Low) | - | - |
| 408 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 34 | C → C | 0.001887 | SNP | Splice Region | UCEC |
| 230 | R → C | 0.007299 | SNP | Missense Mutation | READ |