Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P61163 | ACTR1A; CTRN1 | Alpha-centractin (Centractin) (ARP1) (Actin-RPV) (Centrosome-associated … | Homo sapiens (Human) | 376 aa |
Protein Details: P61163 (ACTR1A)
Protein Information
| Accession | P61163 |
|---|---|
| Protein Names | Alpha-centractin (Centractin) (ARP1) (Actin-RPV) (Centrosome-associated actin homolog) |
| Gene Symbol | ACTR1A; CTRN1 |
| Organism | Homo sapiens (Human) |
| Length | 376 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 33636221 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
6
HAP1 cells
Specificity: 0.667
6/10 (60.0%)
2
Cerebral cortex
Specificity: 0.222
2/4 (50.0%)
1
Liver membrane
Specificity: 0.111
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MESYDVIANQ11PVVIDNGSGV21IKAGFAGDQI31PKYCFPNYVG41RPKHVRVMAG
51-10051ALEGDIFIGP61KAEEHRGLLS71IRYPMEHGIV81KDWNDMERIW91QYVYSKDQLQ
101-150101TFSEEHPVLL111TEAPLNPRKN121RERAAEVFFE131TFNVPALFIS141MQAVLSLYAT
151-200151GRTTGVVLDS161GDGVTHAVPI171YEGFAMPHSI181MRIDIAGRDV191SRFLRLYLRK
201-250201EGYDFHSSSE211FEIVKAIKER221ACYLSINPQK231DETLETEKAQ241YYLPDGSTIE
251-300251IGPSRFRAPE261LLFRPDLIGE271ESEGIHEVLV281FAIQKSDMDL291RRTLFSNIVL
301-350301SGGSTLFKGF311GDRLLSEVKK321LAPKDVKIRI331SAPQERLYST341WIGGSILASL
351-376351DTFKKMWVSK361KEYEEDGARS371IHRKTF
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 34 | Prediction (Low) | - | - |
| 222 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 18 | S → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 46 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 140 | S → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 197 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 241 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 252 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 281 | F → C | 0.002506 | SNP | Missense Mutation | COAD |
| 292 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 292 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 376 | F → C | 0.001887 | SNP | Missense Mutation | UCEC |